Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 6/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 4/20 | 0.41 |
| ▸ | MMP8 | P22894 | 5/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558486 | 0.92 | MMP9 (0.52) | MMP9MMP2MMP1MMP3MMP14 | |
| SCHEMBL5552039 | 0.91 | MMP2 (0.42) | SMN1; SMN2MMP9MMP2MMP1MMP3 | |
| SCHEMBL5552917 | 0.83 | MMP9 (0.54) | MMP9MMP2MMP1MMP3MMP14 | |
| SCHEMBL5552386 | 0.83 | MMP9 (0.54) | MMP9MMP2MMP1MMP3MMP14 | |
| SCHEMBL5552389 | 0.83 | MMP9 (0.54) | MMP9MMP2MMP1MMP3MMP14 | |
| SCHEMBL5552883 | 0.82 | GPR88 (0.52) | SMN1; SMN2ALDH1A1MMP9MMP2MMP1 | |
| SCHEMBL5556746 | 0.77 | TACR3 (0.52) | MMP9MMP2MMP1MMP3MMP14 | |
| SCHEMBL5556724 | 0.75 | MMP9 (0.43) | MMP9MMP2MMP1MMP3MMP14 | |
| SCHEMBL5558617 | 0.75 | MMP9 (0.60) | SMN1; SMN2MMP9MMP2MMP1MMP3 | |
| SCHEMBL5556464 | 0.75 | MMP9 (0.60) | SMN1; SMN2MMP9MMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
| WO-2005027856-A2 | INHIBITORS OF ANTHRAX LETHAL FACTOR | CENGENT THERAPEUTICS (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | SMN1; SMN2 4310/4885ALDH1A1 4059/4885MMP9 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.