Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556573 | 0.85 | MME (0.49) | OPRD1HPGDSMMETPH1 | |
| SCHEMBL12038997 | 0.84 | LTA4H (0.62) | MMEFCER2ERAP2ERAP1LNPEP | |
| SCHEMBL31185441 | 0.84 | LTA4H (0.62) | MMEFCER2ERAP2ERAP1LNPEP | |
| SCHEMBL30626017 | 0.84 | LTA4H (0.62) | MMEFCER2ERAP2ERAP1LNPEP | |
| SCHEMBL2487473 | 0.84 | LTA4H (0.62) | MMEFCER2ERAP2ERAP1LNPEP | |
| SCHEMBL12057953 | 0.84 | LTA4H (0.62) | MMEFCER2ERAP2ERAP1LNPEP | |
| SCHEMBL5552437 | 0.83 | MMP1 (0.54) | — | |
| SCHEMBL5556853 | 0.83 | MMP9 (0.57) | FCER2 | |
| Acetic Acid SCHEMBL31115148 | 0.82 | LTA4H (0.61) | OPRD1MMEFCER2ERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL31115145 | 0.82 | LTA4H (0.61) | OPRD1MMEFCER2ERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | OPRD1 4812/4885HPGDS 533/4885MME 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.