Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276313 | 0.82 | ATM (0.39) | KDM4ENPC1MEN1KMT2ALMNA | |
| SCHEMBL8333545 | 0.81 | LIPG (0.43) | KDM4ENPC1MEN1KMT2ALMNA | |
| SCHEMBL5552085 | 0.80 | ALDH1A1 (0.35) | KDM4ENPC1MEN1KMT2ALMNA | |
| Bicarbonate SCHEMBL5276729 | 0.79 | GAA (0.39) | KDM4EMEN1KMT2ALMNATP53 | |
| SCHEMBL5276721 | 0.78 | ALDH1A1 (0.37) | KDM4EMEN1KMT2ATP53BRD4 | |
| SCHEMBL5551967 | 0.78 | KDM4E (0.38) | KDM4EKMT2ATP53BRD4MAOB | |
| SCHEMBL5557697 | 0.78 | EGLN1 (0.34) | KDM4ETP53BRD4MAOBALDH1A1 | |
| SCHEMBL5555815 | 0.78 | HPGD (0.35) | KDM4ENPC1MEN1KMT2ALMNA | |
| SCHEMBL6858810 | 0.77 | LIPG (0.47) | KDM4ENPC1MEN1KMT2ATP53 | |
| SCHEMBL13339884 | 0.76 | SPHK2 (0.48) | KDM4ENPC1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070003484-A1 | Hydroxypyridinone derivatives, metal complexes thereof and the use thereof for preparing conjugates with biomolecules | SCHERING AG (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20060292079-A1 | Conjugates of hydroxypyridinone derivative metal complexes with biomolecules and their use for MRI diagnosis | EPIX PHARMACEUTICALS, INC. | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060292079-A1 | Conjugates of hydroxypyridinone derivative metal complexes with biomolecules and their use for MRI diagnosis | KLK3, HPGD, HAMP | KDM4E 1907/4885NPC1 4196/4885MEN1 61/4885 |
| US-20070003484-A1 | Hydroxypyridinone derivatives, metal complexes thereof and the use thereof for preparing conjugates with biomolecules | HPD, HAMP, KLK3 | KDM4E 1389/4885NPC1 4437/4885MEN1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.