Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL556030 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL28990684 | 0.69 | ADRB1 (0.34) | — | |
| SCHEMBL28990738 | 0.69 | ADRB1 (0.34) | — | |
| SCHEMBL18284609 | 0.68 | PPARG (0.40) | — | |
| SCHEMBL1554435 | 0.67 | PBRM1 (0.41) | CCR1 | |
| SCHEMBL28479915 | 0.67 | MAPK1 (0.38) | — | |
| SCHEMBL555862 | 0.67 | MTNR1A (0.41) | — | |
| SCHEMBL953060 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL27282899 | 0.65 | KMT2A (0.32) | CCR1 | |
| SCHEMBL6304089 | 0.65 | ESR1 (0.37) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035214-A1 | RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035214-A1 | RENIN INHIBITORS | REN, ACE, AGTR1 | CCR1 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.