Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.82 |
| ▸ | MMP8 | P22894 | 12/20 | 0.82 |
| ▸ | MMP9 | P14780 | 11/20 | 0.82 |
| ▸ | MMP1 | P03956 | 10/20 | 0.82 |
| ▸ | MMP7 | P09237 | 2/20 | 0.82 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.82 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.82 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.82 |
| ▸ | MMP3 | P08254 | 1/20 | 0.82 |
| ▸ | MMP12 | P39900 | 1/20 | 0.82 |
| ▸ | MMP13 | P45452 | 1/20 | 0.82 |
| ▸ | MMP14 | P50281 | 1/20 | 0.82 |
| ▸ | MMP15 | P51511 | 1/20 | 0.82 |
| ▸ | MMP16 | P51512 | 1/20 | 0.82 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.82 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.82 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.82 |
| ▸ | MMP17 | Q9ULZ9 | 1/20 | 0.82 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ilomastat SCHEMBL7870487 | 0.90 | MMP2 (1.00) | MMP2MMP8MMP9MMP1MMP7 | |
| Ilomastat SCHEMBL29412562 | 0.90 | MMP2 (1.00) | MMP2MMP8MMP9MMP1MMP7 | |
| Ilomastat SCHEMBL6691646 | 0.90 | MMP2 (1.00) | MMP2MMP8MMP9MMP1MMP7 | |
| Ilomastat SCHEMBL13575799 | 0.90 | MMP2 (1.00) | MMP2MMP8MMP9MMP1MMP7 | |
| Ilomastat SCHEMBL8190117 | 0.90 | MMP2 (1.00) | MMP2MMP8MMP9MMP1MMP7 | |
| Ilomastat SCHEMBL4394885 | 0.90 | MMP2 (1.00) | MMP2MMP8MMP9MMP1MMP7 | |
| Ilomastat SCHEMBL4293696 | 0.90 | MMP2 (1.00) | MMP2MMP8MMP9MMP1MMP7 | |
| Ilomastat SCHEMBL35303 | 0.90 | MMP2 (1.00) | MMP2MMP8MMP9MMP1MMP7 | |
| SCHEMBL4845965 | 0.89 | MMP2 (0.84) | MMP2MMP8MMP9MMP1MMP7 | |
| SCHEMBL5060570 | 0.89 | MMP2 (0.83) | MMP2MMP8MMP9MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | MMP2 85/4885MMP8 24/4885MMP9 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.