Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27174939 | 0.85 | CA2 (0.34) | LMNANPSR1TDP1 | |
| SCHEMBL787867 | 0.78 | NPSR1 (0.56) | NPSR1ALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL384644 | 0.76 | TRPV4 (0.38) | LMNANPSR1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL1926045 | 0.76 | ALDH1A1 (0.32) | LMNAALDH1A1HSD17B10TDP1CES1 | |
| SCHEMBL23569857 | 0.74 | PTGS2 (0.32) | ALDH1A1HSD17B10TDP1CES1 | |
| SCHEMBL2459334 | 0.74 | GSK3B (0.38) | ALDH1A1HSD17B10TDP1CES1MEN1 | |
| SCHEMBL1927038 | 0.74 | ALDH1A1 (0.31) | ALDH1A1HSD17B10TDP1CES1 | |
| SCHEMBL1035114 | 0.74 | LMNA (0.32) | LMNANPSR1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL11484963 | 0.74 | LMNA (0.36) | LMNANPSR1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL21963283 | 0.71 | NPSR1 (0.30) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658288-B1 | 2-AMINO-5-BENZOYLTHIAZOLE NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | EP | disclosed |
| US-4148845-A | OIL ADDITIVES | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1979-04-10 | — | — | US | disclosed |
| US-4139417-A | Lubricating oil compositions containing copolymers of olefins or of olefins and non-conjugated dienes with unsaturated derivatives of cyclic imides | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1979-02-13 | — | — | US | disclosed |
| US-4063010-A | LUBRICANT ADDITIVES | SOCIETE NATIONALE ELF AQUITAINE (SNEA) (FR) | 1977-12-13 | — | — | US | disclosed |