Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.53 |
| ▸ | DPYD | Q12882 | 3/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559308 | 1.00 | ATAD2 (0.53) | ATAD2DPYDUBE2NKDM3BKMT2A | |
| Thymine SCHEMBL29232704 | 0.83 | ATAD2 (0.76) | ATAD2DPYDUBE2NKDM3BKMT2A | |
| SCHEMBL65892 | 0.82 | DPYD (0.62) | ATAD2DPYDKMT2AALDH1A1GAA | |
| SCHEMBL15798473 | 0.82 | DPYD (0.62) | ATAD2DPYDKMT2AALDH1A1GAA | |
| SCHEMBL190003 | 0.82 | DPYD (0.62) | ATAD2DPYDKMT2AALDH1A1GAA | |
| SCHEMBL25418259 | 0.76 | ATAD2 (0.60) | ATAD2UBE2NKDM3BKMT2ATDP1 | |
| SCHEMBL25450 | 0.76 | — | — | |
| SCHEMBL28216801 | 0.75 | ATAD2 (0.58) | ATAD2UBE2NKDM3BKMT2ATDP1 | |
| SCHEMBL14793573 | 0.74 | DPYD (0.66) | ATAD2DPYDALDH1A1GAALMNA | |
| Thymine SCHEMBL15323914 | 0.73 | ATAD2 (1.00) | ATAD2DPYDALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271258-B2 | Methods of synthesizing oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection | AGILENT TECHNOLOGIES, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-20060252924-A1 | Methods of synthesizing oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2006-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252924-A1 | Methods of synthesizing oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection | POLL, DNTT, RNGTT | ATAD2 3718/4885DPYD 49/4885UBE2N 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.