Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
| ▸ | GMPS | P49915 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865960 | 0.94 | ADORA3 (0.48) | ADORA2AADORA3EHMT1GMPSPI4KA | |
| SCHEMBL1920532 | 0.94 | ADORA3 (0.48) | ADORA2AADORA3EHMT1GMPSPI4KA | |
| SCHEMBL9231750 | 0.94 | ADORA3 (0.49) | ADORA2AADORA3EHMT1GMPSPI4KA | |
| SCHEMBL29509039 | 0.91 | ADORA3 (0.50) | ADORA2AADORA3EHMT1GMPSPI4KA | |
| Phosphoric Acid SCHEMBL15210131 | 0.89 | EHMT1 (0.46) | ADORA2AADORA3EHMT1GMPSPI4KA | |
| SCHEMBL30629421 | 0.89 | ADORA3 (0.44) | ADORA2AADORA3GMPSPI4KAPI4K2B | |
| SCHEMBL28205583 | 0.87 | ADORA3 (0.50) | ADORA2AADORA3GMPSPI4KAPI4K2B | |
| SCHEMBL2534138 | 0.87 | ADORA3 (0.52) | ADORA2AADORA3EHMT1GMPSPI4KA | |
| SCHEMBL25349321 | 0.86 | ADORA3 (0.49) | ADORA2AADORA3GMPSPI4KAPI4K2B | |
| SCHEMBL4884773 | 0.85 | EHMT1 (0.47) | ADORA2AADORA3EHMT1GMPSPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070160554-A1 | Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same | COGNIS IP MANAGEMENT GMBH (DE) | 2007-07-12 | — | — | US | claimed |
| EP-1680435-A1 | ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES | Cognis IP Management GmbH (DE) | 2006-07-19 | — | — | EP | claimed |
| WO-2005049633-A1 | ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES | COGNIS IP MANAGEMENT GMBH (DE) | 2005-06-02 | — | — | WO | claimed |
| US-20070160554-A1 | Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same | COGNIS IP MANAGEMENT GMBH (DE) | 2007-07-12 | — | — | US | disclosed |
| EP-1680435-A1 | ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES | Cognis IP Management GmbH (DE) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005049633-A1 | ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES | COGNIS IP MANAGEMENT GMBH (DE) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070160554-A1 | Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same | RNASEL, RNASEH1, DUT | ADORA2A 317/4885ADORA3 299/4885EHMT1 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.