Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2115002 | 0.84 | NPC1 (0.40) | P2RX7 | |
| Hydrochloric Acid SCHEMBL2116036 | 0.68 | ALDH1A1 (0.39) | P2RX7 | |
| Hydrochloric Acid SCHEMBL2117447 | 0.61 | POLB (0.40) | P2RX7 | |
| SCHEMBL27653187 | 0.56 | CHRNB2 (0.45) | P2RX7 | |
| SCHEMBL27742860 | 0.53 | L3MBTL1 (0.42) | — | |
| SCHEMBL5104725 | 0.53 | L3MBTL1 (0.42) | P2RX7 | |
| SCHEMBL10150478 | 0.52 | PPM1B (0.44) | — | |
| SCHEMBL14997666 | 0.52 | EPHX2 (0.37) | P2RX7 | |
| SCHEMBL8087999 | 0.52 | — | — | |
| SCHEMBL1122469 | 0.51 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223822-B2 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20040220359-A1 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-04 | — | — | US | disclosed |