SCHEMBL556528

SCHEMBL556528

CCOC(=O)C(C)(C)C(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
LMNA P02545 1/20 0.48
HSD17B10 Q99714 1/20 0.48
PKM P14618 3/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP4F2 P78329 3/20 0.44
CYP4A11 Q02928 3/20 0.44
THRB P10828 1/20 0.44
HTT P42858 1/20 0.42
MMP8 P22894 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALOX15 P16050 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
MAPT P10636 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1562023 0.87 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10PKMKDM4E
Hydrochloric Acid SCHEMBL5446995 0.84 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10PKMKDM4E
Butane SCHEMBL11358505 0.82 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10PKMKDM4E
SCHEMBL25044536 0.81 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10PKMKDM4E
SCHEMBL25975442 0.81 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10PKMKDM4E
SCHEMBL14305396 0.81 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10PKMKDM4E
SCHEMBL1299895 0.80 CYP4F2 (0.44) ALDH1A1LMNAHSD17B10PKMKDM4E
SCHEMBL18654174 0.78 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10PKMKDM4E
SCHEMBL23828946 0.78 MEN1 (0.44) ALDH1A1LMNAHSD17B10PKMKDM4E
Hydrochloric Acid SCHEMBL11066122 0.78 CYP4F2 (0.42) ALDH1A1LMNAHSD17B10PKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116791370-A Breakage-resistant cotton yarn and preparation method thereof 苍南县星辉纺织有限公司 2023-09-22 CN claimed
EP-4081511-B3 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2026-03-04 EP disclosed
WO-2025030117-A1 FERROPTOSIS INDUCERS ARPEGGIO BIOSCIENCES, INC. (US) 2025-02-06 WO disclosed
EP-4442319-A2 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES Sitryx Therapeutics Limited (GB) 2024-10-09 EP disclosed
EP-4081511-B1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2024-07-31 EP disclosed
US-20240245691-A1 2-METHYLENE-4-OXO-BUTANOIC ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATION SITRYX THERAPEUTICS LIMITED (GB) 2024-07-25 US disclosed
EP-4330231-A1 2-METHYLENE-4-OXO-BUTANOIC ACID DRIVATIVES FOR THE TREATMENT OF INFLAMMATION Sitryx Therapeutics Limited (GB) 2024-03-06 EP disclosed
CN-116791370-A Breakage-resistant cotton yarn and preparation method thereof 苍南县星辉纺织有限公司 2023-09-22 CN disclosed
US-20230257367-A1 NOVEL THYROID HORMONE BETA RECEPTOR AGONIST CHENGDU KANGHONG PHARMACEUTICAL CO., LTD. (CN) 2023-08-17 US disclosed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 US disclosed
US-4066780-A Pyranoindole derivatives as antiulcer agents AYERST MCKENNA AND HARRISON LTD. (CA) 1978-01-03 US disclosed
US-4066779-A ANTIDEPRESSANT, ANTIULCER AYERST, MCKENNA AND HARRISON LTD. (CA) 1978-01-03 US disclosed
US-4056538-A ANTIDEPRESSANTS, ANTIULCER AGENTS AYERST, MCKENNA & HARRISON LIMITED (CA) 1977-11-01 US disclosed
US-4041169-A TREATING AND PREVENTING ULCERS AYERST MCKENNA AND HARRISON LTD. (CA) 1977-08-09 US disclosed
US-4035495-A HYPERTENSIVE AGENTS, CNS DEPRESSANT AYERST MCKENNA AND HARRISON LTD. (CA) 1977-07-12 US disclosed
US-4012511-A ANTIULCER AGENTS AYERST MCKENNA & HARRISON LTD. (CA) 1977-03-15 US disclosed
US-4012417-A ACID CATALYSTS AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-15 US disclosed
US-4003913-A ANTIDEPRESSANTS, ANTIULCER AGENTS AYERST MCKENNA AND HARRISON LTD. (CA) 1977-01-18 US disclosed
US-3995052-A Indenopyran- and indenothiopyranalkylamines III in the treatment of depression AYERST MCKENNA AND HARRISON LTD. (CA) 1976-11-30 US disclosed
US-3962236-A ANTIDEPRESSANTS, ANTI-ULCER AYERST MCKENNA AND HARRISON LTD. (CA) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240245691-A1 2-METHYLENE-4-OXO-BUTANOIC ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATION HCAR2, NFKBIA, TNF ALDH1A1 213/4885LMNA 3846/4885HSD17B10 467/4885
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP ALDH1A1 1060/4885LMNA 605/4885HSD17B10 2628/4885
US-20230257367-A1 NOVEL THYROID HORMONE BETA RECEPTOR AGONIST THRB, THRA, TSHR ALDH1A1 1538/4885LMNA 3608/4885HSD17B10 146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.