Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565852 | 0.89 | S1PR1 (0.36) | CSNK2A1S1PR1 | |
| SCHEMBL5565859 | 0.89 | S1PR1 (0.36) | CSNK2A1S1PR1 | |
| SCHEMBL4839632 | 0.81 | CSNK2A1 (0.32) | CSNK2A1S1PR1TRPV3 | |
| SCHEMBL5569939 | 0.80 | CSNK2A1 (0.33) | CSNK2A1S1PR1TRPV3 | |
| SCHEMBL5565634 | 0.80 | GCGR (0.37) | CSNK2A1S1PR1 | |
| SCHEMBL5569744 | 0.79 | THRA (0.36) | CSNK2A1S1PR1 | |
| SCHEMBL5569135 | 0.76 | MEN1 (0.36) | CSNK2A1S1PR1TRPV3 | |
| SCHEMBL5569474 | 0.73 | P2RX3 (0.39) | CSNK2A1S1PR1 | |
| SCHEMBL5565201 | 0.72 | P2RX3 (0.32) | CSNK2A1 | |
| SCHEMBL5565205 | 0.72 | P2RX3 (0.32) | CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | claimed |
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | CSNK2A1 401/4885S1PR1 2943/4885TRPV3 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.