Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565856 | 0.81 | CSNK2A1 (0.33) | CSNK2A1TRPV3S1PR1 | |
| SCHEMBL4880126 | 0.74 | FAAH (0.32) | CSNK2A1TRPV3 | |
| SCHEMBL4776899 | 0.74 | MEN1 (0.37) | CSNK2A1TRPV3 | |
| SCHEMBL5565852 | 0.69 | S1PR1 (0.36) | CSNK2A1S1PR1 | |
| SCHEMBL5565859 | 0.69 | S1PR1 (0.36) | CSNK2A1S1PR1 | |
| SCHEMBL5569436 | 0.65 | CSNK2A1 (0.41) | CSNK2A1S1PR1 | |
| SCHEMBL5569431 | 0.65 | CSNK2A1 (0.41) | CSNK2A1S1PR1 | |
| SCHEMBL4718876 | 0.63 | CENPE (0.36) | — | |
| SCHEMBL4722601 | 0.63 | GCGR (0.43) | CSNK2A1 | |
| SCHEMBL4777487 | 0.62 | PPARG (0.43) | CSNK2A1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |