Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2328390 | 0.81 | TDP1 (0.54) | POLBL3MBTL1MAPTTDP1HDAC3 | |
| SCHEMBL5094452 | 0.80 | PTGS2 (0.48) | POLBMAPTCYP2D6SRCLMNA | |
| SCHEMBL7309314 | 0.78 | CYP2D6 (0.41) | POLBMAPTCYP2D6SRCKMT2A | |
| SCHEMBL25858677 | 0.78 | LMNA (0.42) | CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL2328394 | 0.77 | TDP1 (0.50) | POLBL3MBTL1MAPTTDP1HDAC3 | |
| SCHEMBL7367258 | 0.77 | SRC (0.50) | POLBMAPTCYP2D6SRCKMT2A | |
| SCHEMBL27791494 | 0.75 | LMNA (0.55) | POLBMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL13316976 | 0.74 | ATM (0.41) | L3MBTL1CYP2D6SRCKMT2AMEN1 | |
| SCHEMBL396389 | 0.73 | L3MBTL1 (0.56) | POLBL3MBTL1TDP1HDAC3HDAC4 | |
| Diphenylacetic Acid SCHEMBL11774892 | 0.73 | SRC (0.56) | POLBL3MBTL1TDP1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980169-A | Synthetic method of modafinil | HEBEI KANGTAI PHARMACEUTICAL CO LTD | 2014-08-13 | — | — | CN | disclosed |
| US-20130203709-A1 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | THE PENN STATE RESEARCH FOUNDATION (US) | 2013-08-08 | — | — | US | disclosed |
| CN-101440053-B | Preparation of benzhydryl thioacetamide | CHONGQING KANGLE PHARMACEUTICAL CO LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-100534979-C | Synthesis method of modafinil | ZHEJIANG HUANA PHARMACEUTICAL (CN) | 2009-09-02 | — | — | CN | disclosed |
| CN-101440053-A | Preparation of benzhydryl thioacetamide | CHONGQING KANGLE PHARMACEUTICA (CN) | 2009-05-27 | — | — | CN | disclosed |
| CN-1986527-A | Novel method for synthesizing modafinil | ZHEJIANG HUANA PHARMACEUTICAL (CN) | 2007-06-27 | — | — | CN | disclosed |
| US-7211684-B2 | Method for preparing methyl 2-diphenylmethylsulfinylacetate | CEPHALON FRANCE (FR) | 2007-05-01 | — | — | US | disclosed |
| US-20060235237-A1 | Method for preparing methyl 2-diphenylmethylsulfinylacetate | TEVA SANTE (FR) | 2006-10-19 | — | — | US | disclosed |
| EP-1583739-A1 | METHOD FOR PREPARING METHYL 2-DIPHENYLMETHYLSULFINYLACETATE | Organisation de Synthese Mondiale Orsymonde (FR) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004063149-A1 | METHOD FOR PREPARING METHYL 2-DIPHENYLMETHYLSULFINYLACETATE | ORGANISATION DE SYNTHESE MONDIALE ORSYMONDE (FR) | 2004-07-29 | — | — | WO | disclosed |
| EP-1437345-A1 | Novel method for preparing methyl 2-diphenylmethylsulfinylacetate | Organisation de Synthese Mondiale Orsymonde (FR) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235237-A1 | Method for preparing methyl 2-diphenylmethylsulfinylacetate | MTR, TST, MSMO1 | POLB 682/4885L3MBTL1 2257/4885MAPT 2741/4885 |
| US-20130203709-A1 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME | BCL2, BCL2L2, BCL6 | POLB 4401/4885L3MBTL1 2010/4885MAPT 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.