Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115204 | 0.81 | KMO (0.36) | — | |
| SCHEMBL5563298 | 0.80 | POLB (0.35) | — | |
| SCHEMBL7109630 | 0.77 | CSF1R (0.38) | — | |
| SCHEMBL6636112 | 0.76 | PGR (0.32) | — | |
| SCHEMBL7113378 | 0.76 | ABL1 (0.38) | — | |
| SCHEMBL17336825 | 0.75 | RXFP1 (0.35) | — | |
| SCHEMBL7112784 | 0.75 | SCN5A (0.35) | SYK | |
| SCHEMBL7047983 | 0.75 | AAK1 (0.33) | SYK | |
| SCHEMBL17336851 | 0.74 | POLB (0.35) | RXRA | |
| SCHEMBL7117074 | 0.74 | ABL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474416-B1 | DIHYDROBENZODIAZEPIN-2-ONE-DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | HOFFMANN LA ROCHE (CH) | 2007-09-26 | — | — | EP | disclosed |