Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568619 | 0.91 | ALDH1A1 (0.42) | SPRCYP3A4CYP2C9FASNALDH1A1 | |
| SCHEMBL5564813 | 0.89 | HCAR2 (0.43) | SPRCYP3A4CYP2C9RIPK1HCAR2 | |
| SCHEMBL5567085 | 0.87 | CYP3A4 (0.41) | CYP3A4CYP2C9RIPK1HCAR2KDM4E | |
| SCHEMBL5567457 | 0.85 | CYP3A4 (0.40) | SPRCYP3A4CYP2C9RIPK1HCAR2 | |
| SCHEMBL5564848 | 0.85 | CYP3A4 (0.40) | CYP3A4CYP2C9RIPK1HCAR2ALDH1A1 | |
| SCHEMBL5567092 | 0.83 | CYP3A4 (0.39) | CYP3A4CYP2C9HCAR2ALDH1A1KDM4E | |
| SCHEMBL4599450 | 0.80 | CYP3A4 (0.60) | SPRCYP3A4CYP2C9RIPK1F11 | |
| SCHEMBL4599571 | 0.80 | CYP3A4 (0.60) | SPRCYP3A4CYP2C9RIPK1F11 | |
| SCHEMBL5567826 | 0.79 | CYP3A4 (0.42) | CYP3A4CYP2C9HCAR2MEN1KMT2A | |
| SCHEMBL5567838 | 0.78 | CYP3A4 (0.41) | CYP3A4CYP2C9RIPK1HCAR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203114-A1 | 7,8,9,10-Tetrahydro-Imidazo [2,1-A] Isochinolines | ALTANA PHARMA AG (DE) | 2007-08-30 | — | — | US | disclosed |
| EP-1805173-A2 | 7, 8, 9, 10- TETRAHYDRO-IMIDAZO [2,1-A] ISOQUINOLINE DERIVATIVES AND THEIR USE AS GASTRIC ACID SECRETION INHIBITORS | Altana Pharma AG (DE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2005090346-A2 | 7, 8, 9, 10- TETRAHYDRO-IMIDAZO [2,1-A] ISOQUINOLINE DERIVATIVES AND THEIR USE AS GASTRIC ACID SECRETION INHIBITORS | ALTANA PHARMA AG (DE) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203114-A1 | 7,8,9,10-Tetrahydro-Imidazo [2,1-A] Isochinolines | GIPR, CCKBR, SLC10A2 | SPR 4233/4885CYP3A4 292/4885CYP2C9 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.