Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564813 | 0.89 | HCAR2 (0.43) | CYP3A4CYP2C9HCAR2RIPK1NPC1 | |
| SCHEMBL5567085 | 0.88 | CYP3A4 (0.41) | CYP3A4CYP2C9HCAR2RIPK1NPC1 | |
| SCHEMBL5567457 | 0.86 | CYP3A4 (0.40) | CYP3A4CYP2C9HCAR2RIPK1NPC1 | |
| SCHEMBL5567700 | 0.85 | SPR (0.41) | CYP3A4CYP2C9HCAR2RIPK1NPC1 | |
| SCHEMBL5567092 | 0.84 | CYP3A4 (0.39) | CYP3A4CYP2C9HCAR2NPC1RAB9A | |
| SCHEMBL5568619 | 0.82 | ALDH1A1 (0.42) | CYP3A4CYP2C9NPC1RAB9AKDM4E | |
| SCHEMBL5566450 | 0.81 | ATP4A (0.44) | CYP3A4CYP2C9RIPK1SCD5CCNA2 | |
| SCHEMBL5570682 | 0.81 | ATP4A (0.44) | CYP3A4CYP2C9RIPK1SCD5CCNA2 | |
| SCHEMBL5567363 | 0.81 | ATP4A (0.44) | CYP3A4CYP2C9RIPK1SCD5CCNA2 | |
| SCHEMBL4601224 | 0.80 | CYP3A4 (0.61) | CYP3A4CYP2C9RIPK1SCD5CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203114-A1 | 7,8,9,10-Tetrahydro-Imidazo [2,1-A] Isochinolines | ALTANA PHARMA AG (DE) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203114-A1 | 7,8,9,10-Tetrahydro-Imidazo [2,1-A] Isochinolines | GIPR, CCKBR, SLC10A2 | CYP3A4 292/4885CYP2C9 112/4885HCAR2 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.