Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567700 | 0.91 | SPR (0.41) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL5564813 | 0.86 | HCAR2 (0.43) | NPC1RAB9ATSHRPOLBHSD17B10 | |
| SCHEMBL5567085 | 0.84 | CYP3A4 (0.41) | KDM4ENPC1RAB9ATSHRPOLB | |
| SCHEMBL5564848 | 0.82 | CYP3A4 (0.40) | ALDH1A1KDM4ETP53NPC1RAB9A | |
| SCHEMBL5567457 | 0.82 | CYP3A4 (0.40) | ALDH1A1KDM4ENPC1RAB9ACYP3A4 | |
| SCHEMBL4600155 | 0.81 | CYP3A4 (0.57) | ALDH1A1KDM4ETP53SMN1; SMN2NPC1 | |
| SCHEMBL4599316 | 0.81 | CYP3A4 (0.57) | ALDH1A1KDM4ETP53SMN1; SMN2NPC1 | |
| SCHEMBL5567092 | 0.81 | CYP3A4 (0.39) | ALDH1A1KDM4ETP53SMN1; SMN2NPC1 | |
| SCHEMBL5567826 | 0.76 | CYP3A4 (0.42) | TSHRPOLBHSD17B10CYP3A4CYP2C9 | |
| SCHEMBL5567838 | 0.76 | CYP3A4 (0.41) | NPC1RAB9ATSHRPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203114-A1 | 7,8,9,10-Tetrahydro-Imidazo [2,1-A] Isochinolines | ALTANA PHARMA AG (DE) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203114-A1 | 7,8,9,10-Tetrahydro-Imidazo [2,1-A] Isochinolines | GIPR, CCKBR, SLC10A2 | ALDH1A1 164/4885KDM4E 3648/4885TP53 3602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.