Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 11/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL922192 | 0.85 | ANO1 (0.46) | NLRP3ANO1SRCNPY5R | |
| SCHEMBL4041104 | 0.78 | ANO1 (0.44) | NLRP3ANO1NPY5R | |
| SCHEMBL4035815 | 0.76 | JAK2 (0.55) | NLRP3ROCK1 | |
| Hydrochloric Acid SCHEMBL921534 | 0.75 | JAK2 (0.54) | NLRP3ROCK1 | |
| SCHEMBL4423340 | 0.72 | EPHX2 (0.71) | NLRP3SELPSELE | |
| SCHEMBL8349809 | 0.71 | NLRP3 (0.58) | NLRP3ANO1SELPSELE | |
| SCHEMBL4423342 | 0.69 | NLRP3 (0.75) | NLRP3 | |
| SCHEMBL29520161 | 0.69 | NLRP3 (0.75) | NLRP3 | |
| SCHEMBL5106834 | 0.69 | NLRP3 (0.62) | NLRP3 | |
| SCHEMBL5114611 | 0.69 | NLRP3 (0.74) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232620-A1 | 3-Aminoindazoles | MERCK PATENT GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232620-A1 | 3-Aminoindazoles | SGK3, SGK1, SGK2 | NLRP3 831/4885ANO1 1634/4885ROCK1 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.