Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573417 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL5569137 | 0.70 | KMT2A (0.42) | ALDH1A1 | |
| SCHEMBL31092010 | 0.66 | — | — | |
| SCHEMBL5573413 | 0.66 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL20609645 | 0.62 | ALDH1A1 (0.58) | ALDH1A1TDP1 | |
| SCHEMBL4252557 | 0.61 | ALDH1A1 (0.65) | ALDH1A1TDP1 | |
| SCHEMBL1024003 | 0.61 | ALDH1A1 (0.65) | ALDH1A1TDP1 | |
| Sulfur Dioxide SCHEMBL6157253 | 0.60 | ALDH1A1 (0.73) | ALDH1A1TDP1 | |
| SCHEMBL473081 | 0.60 | ALDH1A1 (1.00) | ALDH1A1TDP1 | |
| SCHEMBL7639 | 0.60 | ALDH1A1 (1.00) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7226906-B2 | Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases | ARRAY BIOPHARMA, INC. (US) | 2007-06-05 | — | — | US | disclosed |
| WO-2006023452-A2 | CYCLOSPORIN ANALOGS FOR THE TREATMENT OF IMMUNOREGULATORY DISORDERS AND RESPIRATORY DISEASES | ARRAY BIOPHARMA INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060035821-A1 | Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases | ARRAY BIOPHARMA INC. | 2006-02-16 | — | — | US | disclosed |
| US-20060035822-A1 | Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases | ARRAY BIOPHARMA INC. | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035821-A1 | Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases | TSLP, CHP1, IL2 | ALDH1A1 3651/4885TDP1 2616/4885 |
| US-20060035822-A1 | Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases | TSLP, CHP1, IL2 | ALDH1A1 3651/4885TDP1 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.