Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544747 | 0.81 | GPR3 (0.34) | GPR3HTR2A | |
| SCHEMBL5573163 | 0.80 | GPR3 (0.41) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL6545167 | 0.77 | MEN1 (0.33) | GPR3 | |
| SCHEMBL8587289 | 0.75 | HTR2A (0.42) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL9602938 | 0.68 | GPR3 (0.34) | GPR3HTR2A | |
| SCHEMBL8661771 | 0.65 | HTR2A (0.39) | HTR2A | |
| SCHEMBL2547987 | 0.62 | ACHE (0.39) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL2546805 | 0.62 | ACHE (0.47) | ACHEBCHEHTR2ACHRM2HTR1A | |
| SCHEMBL6544498 | 0.62 | GPR3 (0.46) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL29162236 | 0.61 | MAOA (0.47) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057174-B1 | NEW CYCLOPENTADIENYL, INDENYL OR FLUORENYL SUBSTITUTED PHOSPHINE COMPOUNDS AND THEIR USE IN CATALYTIC REACTIONS | EVONIK DEGUSSA GMBH (DE) | 2014-12-17 | — | — | EP | disclosed |
| US-7169865-B2 | Transition metal compounds having a donor-acceptor interaction and a specific substitution pattern | BAYER AKTIENGESELLSCHAFT (DE) | 2007-01-30 | — | — | US | disclosed |
| US-7169866-B2 | Process for preparing homopolymers, copolymers and/or block copolymers by living polymerization with metallocenes having a donor-acceptor interaction | BAYER AKTIENGESELLSCHAFT (DE) | 2007-01-30 | — | — | US | disclosed |
| EP-1549683-A1 | METHOD FOR PRODUCING HOMOPOLYMERS, COPOLYMERS AND/OR BLOCK COPOLYMERS COMPRISING METALLOCENES WITH A DONOR-ACCEPTOR INTERACTION, ACCORDING TO A LIVING POLYMERISATION PROCESS | Lanxess Deutschland GmbH (DE) | 2005-07-06 | — | — | EP | disclosed |
| EP-1546165-A1 | TRANSITION METAL COMPOUNDS WITH DONOR-ACCEPTOR INTERACTION AND A SPECIAL SUBSTITUTION PATTERN | Lanxess Deutschland GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004029100-A1 | METHOD FOR PRODUCING HOMOPOLYMERS, COPOLYMERS AND/OR BLOCK COPOLYMERS COMPRISING METALLOCENES WITH A DONOR-ACCEPTOR INTERACTION, ACCORDING TO A LIVING POLYMERISATION PROCESS | LANXESS DEUTSCHLAND GMBH (DE) | 2004-04-08 | — | — | WO | disclosed |
| WO-2004029065-A1 | TRANSITION METAL COMPOUNDS WITH DONOR-ACCEPTOR INTERACTION AND A SPECIAL SUBSTITUTION PATTERN | LANXESS DEUTSCHLAND GMBH (DE) | 2004-04-08 | — | — | WO | disclosed |
| US-20040063877-A1 | Process for preparing homopolymers, copolymers and/or block copolymers by living polymerization with metallocenes having a donor-acceptor interaction | LANXESS DEUTSCHLAND GMBH (DE) | 2004-04-01 | — | — | US | disclosed |
| US-20040059073-A1 | Transition metal compounds having a donor-acceptor interaction and a specific substitution pattern | LANXESS DEUTSCHLAND GMBH (DE) | 2004-03-25 | — | — | US | disclosed |
| EP-1373284-A1 | CATALYSTS CHARACTERIZED BY A DONOR-ACCEPTOR INTERACTION | Bayer Aktiengesellschaft (DE) | 2004-01-02 | — | — | EP | disclosed |
| US-6657027-B2 | Compounds in which a transition metal is complexed with two ligand systems that systems are reversibly bonded together by a bridge ofa donor and an acceptor; at least one fluorinated aryl radical; olefin polymerization catalysts | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-02 | — | — | US | disclosed |
| US-20030036474-A1 | Catalysts with a donor-acceptor interaction | LANXESS DEUTSCHLAND GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
| WO-2002076999-A1 | CATALYSTS CHARACTERIZED BY A DONOR-ACCEPTOR INTERACTION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | WO | disclosed |