Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570859 | 0.87 | EP300 (0.49) | NPC1RAB9AKDM4EMAPTGUSB | |
| SCHEMBL179797 | 0.78 | CCR4 (0.43) | KDM4EMAPTEP300ALDH1A1HPGD | |
| SCHEMBL179732 | 0.76 | NPC1 (0.58) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL60856 | 0.69 | AURKA (0.66) | NPC1RAB9AKDM4EMAPTGUSB | |
| SCHEMBL30601531 | 0.69 | NPC1 (0.51) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL484174 | 0.68 | AURKA (0.64) | NPC1RAB9AKDM4EMAPTGUSB | |
| SCHEMBL484484 | 0.66 | NPC1 (0.61) | NPC1RAB9AKDM4EMAPTGUSB | |
| SCHEMBL4494231 | 0.64 | MAPT (0.80) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL30349923 | 0.64 | MAPT (0.80) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL7750137 | 0.64 | EP300 (0.78) | NPC1RAB9AKDM4EMAPTEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282327-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2007-10-16 | — | — | US | claimed |