SCHEMBL179797

SCHEMBL179797

Cc1oc(=O)c(N2C(=O)C=CC2=O)c2cc(N(C)C)ccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 1/20 0.43
KDM4E B2RXH2 4/20 0.40
EP300 Q09472 1/20 0.37
CA12 O43570 1/20 0.36
CA9 Q16790 1/20 0.36
ELANE P08246 3/20 0.35
ALDH1A1 P00352 4/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
MAPT P10636 2/20 0.34
PDE3B Q13370 1/20 0.34
PDE3A Q14432 1/20 0.34
THRB P10828 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
SNCA P37840 1/20 0.33
SLC16A3 O15427 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29527262 0.80 CCR4 (0.64) CCR4KDM4EEP300CA12CA9
SCHEMBL179796 0.80 CCR4 (0.64) CCR4KDM4EEP300CA12CA9
SCHEMBL13730668 0.78 HSP90AA1 (0.30) EP300HSP90AA1MGLL
SCHEMBL7750137 0.66 EP300 (0.78) CCR4KDM4EEP300CA12CA9
SCHEMBL3363523 0.66 EP300 (0.69) CCR4KDM4EEP300ALDH1A1HPGD
SCHEMBL4534137 0.63 EP300 (0.43) CCR4KDM4EEP300ALDH1A1HPGD
SCHEMBL10881037 0.63 CCR4 (0.62) CCR4KDM4EALDH1A1HPGDMAPT
SCHEMBL10433675 0.63 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL3759716 0.63 MGLL (0.65) KDM4EALDH1A1HSD17B10MAPTNPSR1
SCHEMBL5048528 0.61 GAA (0.35) CCR4KDM4EEP300ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076072-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2011-12-13 US claimed
US-8026057-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2011-09-27 US claimed
US-7468243-B2 Nucleotide sequence labelling compoumd four use as tool in genetic engineering AFFYMETRIX, INC. (US) 2008-12-23 US claimed
US-7282327-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-10-16 US claimed
US-12297221-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2025-05-13 US disclosed
US-11993772-B2 Linking sequence reads using paired code tags ILLUMINA, INC. (US) 2024-05-28 US disclosed
US-20230406874-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE ILLUMINA, INC. 2023-12-21 US disclosed
US-11760772-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2023-09-19 US disclosed
US-20210277043-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE ILLUMINA, INC. (US) 2021-09-09 US disclosed
US-11021504-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2021-06-01 US disclosed
US-11008567-B2 Oligonucleotide replacement for di-tagged and directional libraries ILLUMINA, INC. (US) 2021-05-18 US disclosed
EP-3722423-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE Illumina, Inc. (US) 2020-10-14 EP disclosed
US-4318707-A IMMUNOASSAY EMPLOYING ABSORPTION PARTICLES SYVA COMPANY (US) 1982-03-09 US disclosed
EP-0046004-A1 Concentrating zone method in heterogeneous immunoassays SYVA COMPANY (US) 1982-02-17 EP disclosed
US-4281061-A DETECTABLE SIGNAL FROM FLUORESCENT DYE OR LABELED ENZYME SYVA COMPANY (US) 1981-07-28 US disclosed
US-4272506-A BINDING A LABELED MEMBER OF A SPECIFIC BINDING PAIR TO A MERCAPTO-ACTIVATED SUPPORT THROUGH CLEAVABLE DISULFIDE LINKAGES; IMMUNOASSAY; ACCURACY SYVA COMPANY (US) 1981-06-09 US disclosed
US-4256834-A REPRESSING THE SIGNALS PRODUCED BY UNBOUND LABELS; SENSITIVITY SYVA COMPANY (US) 1981-03-17 US disclosed
EP-0017908-A1 A method for determining the presence in a sample of an analyte and a kit for use in this method SYVA COMPANY (US) 1980-10-29 EP disclosed
EP-0015695-A1 Support-ligand analog-fluorescer conjugate and serum assay method involving such conjugate SYVA COMPANY (US) 1980-09-17 EP disclosed
US-4193983-A Labeled liposome particle compositions and immunoassays therewith SYVA COMPANY (US) 1980-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230406874-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE PHAX, ALKBH1, JMJD6 CCR4 1019/4885KDM4E 931/4885EP300 1847/4885
US-11021504-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 CCR4 1019/4885KDM4E 931/4885EP300 1847/4885
US-20210277043-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE PHAX, ALKBH1, JMJD6 CCR4 1019/4885KDM4E 931/4885EP300 1847/4885
US-12297221-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 CCR4 1019/4885KDM4E 931/4885EP300 1847/4885
US-11760772-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 CCR4 1019/4885KDM4E 931/4885EP300 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.