Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20810767 | 0.79 | IDO1 (0.42) | ALOX15TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL22580949 | 0.77 | CA2 (0.41) | ALOX15TSHRALDH1A1TDP1CA2 | |
| SCHEMBL4964367 | 0.74 | ALOX15 (0.48) | ALOX15TSHRALDH1A1TDP1CA2 | |
| SCHEMBL6741742 | 0.72 | PLAU (0.38) | ALOX15TSHRALDH1A1TDP1CA2 | |
| SCHEMBL3666211 | 0.70 | POLB (0.46) | ALOX15TSHRALDH1A1TDP1HPGD | |
| SCHEMBL7254610 | 0.69 | TSHR (0.43) | ALOX15TSHRCA2HPGDHSD17B10 | |
| SCHEMBL7250609 | 0.69 | TSHR (0.43) | ALOX15TSHRALDH1A1CA2HPGD | |
| SCHEMBL7083086 | 0.69 | CXCR2 (0.49) | ALOX15TSHRALDH1A1TDP1HPGD | |
| SCHEMBL7251745 | 0.69 | ALDH1A1 (0.38) | ALOX15TSHRALDH1A1CA2CA1 | |
| Hydrochloric Acid SCHEMBL9012929 | 0.68 | KDM4E (0.44) | TSHRALDH1A1TDP1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7258702-B2 | Yellow cationic dyes for dyeing of organic material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-08-21 | — | — | US | disclosed |
| US-20050000034-A1 | Yellow cationic dyes for dyeing of organic material | CIBA SPECIALTY CHEMICALS CORPORATION | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050000034-A1 | Yellow cationic dyes for dyeing of organic material | KRT18, PYCR1, CYC1 | ALOX15 2719/4885TSHR 2334/4885ALDH1A1 3276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.