Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 8/20 | 0.58 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | HINT1 | P49773 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16822243 | 1.00 | STING1 (0.58) | STING1PDE3BPDE3AADORA3PNP | |
| SCHEMBL21162740 | 1.00 | STING1 (0.58) | STING1PDE3BPDE3AADORA3PNP | |
| SCHEMBL6551940 | 0.98 | STING1 (0.58) | STING1PDE3BPDE3AADORA3PNP | |
| SCHEMBL20673214 | 0.86 | ADORA3 (0.52) | STING1PDE3BPDE3AADORA3ADORA2A | |
| SCHEMBL19417833 | 0.84 | STING1 (0.52) | STING1PDE3BPDE3AADORA3HINT1 | |
| SCHEMBL24772604 | 0.83 | STING1 (0.49) | STING1PDE3BPDE3AADORA3PNP | |
| SCHEMBL23600855 | 0.81 | STING1 (0.56) | STING1ADORA3ADORA2A | |
| SCHEMBL18661220 | 0.81 | ADORA3 (0.47) | STING1PDE3BPDE3AADORA3ADORA2A | |
| SCHEMBL8885117 | 0.81 | PNP (0.60) | STING1PDE3BPDE3AADORA3PNP | |
| SCHEMBL7030275 | 0.80 | HINT1 (0.63) | PNPHINT1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476690-A1 | Compounds and pharmaceutical compositions for the treatment of viral infections | IDENIX Pharmaceuticals, Inc. (US) | 2012-07-18 | — | — | EP | disclosed |
| US-20120107867-A1 | GLYCOPEGYLATED ERYTHROPOIETIN | NOVO NORDISK A/S (DK) | 2012-05-03 | — | — | US | disclosed |