SCHEMBL23600855

SCHEMBL23600855

O=c1[nH]cnc2c1ncn2C1OCC(O)C1O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 6/20 0.56
▸ ADORA3 P0DMS8 4/20 0.55
▸ ALDH1A1 P00352 1/20 0.51
▸ LMNA P02545 1/20 0.51
▸ ALB P02768 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ TYMP P19971 3/20 0.51
▸ P2RX3 P56373 1/20 0.51
▸ GSK3A P49840 2/20 0.47
▸ RPS6KA3 P51812 2/20 0.47
▸ MAPK14 Q16539 2/20 0.47
▸ ADORA2A P29274 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28772469 0.97 STING1 (0.56) STING1ADORA3ALDH1A1LMNAALB
SCHEMBL21162740 0.81 STING1 (0.58) STING1ADORA3ADORA2A
SCHEMBL16822243 0.81 STING1 (0.58) STING1ADORA3ADORA2A
SCHEMBL5571313 0.81 STING1 (0.58) STING1ADORA3ADORA2A
SCHEMBL6551940 0.79 STING1 (0.58) STING1ADORA3GSK3ARPS6KA3MAPK14
SCHEMBL31170758 0.79 P2RX3 (0.61) STING1ADORA3ALDH1A1LMNAALB
SCHEMBL8883524 0.79 AHCY (0.60) STING1ADORA3ALDH1A1LMNAALB
SCHEMBL20309498 0.78 STING1 (0.58) STING1ADORA3ALDH1A1LMNAALB
SCHEMBL7033376 0.77 ADORA3 (0.44) STING1ADORA3ALDH1A1TYMPP2RX3
SCHEMBL4276795 0.77 ADORA3 (0.51) STING1ADORA3ALDH1A1LMNAALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210198673-A1 RNA TARGETING OF MUTATIONS VIA SUPPESSOR tRNAs AND DEAMINASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-07-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198673-A1 RNA TARGETING OF MUTATIONS VIA SUPPESSOR tRNAs AND DEAMINASES UPF1, RNASE1, TARBP1 STING1 202/4885ADORA3 2627/4885ALDH1A1 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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