Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573716 | 1.00 | CCR5 (0.38) | CCR5NSD3RIPK1SLC18A3SIGMAR1 | |
| SCHEMBL4597902 | 0.86 | CCR5 (0.44) | CCR5NSD3RIPK1SLC18A3SIGMAR1 | |
| SCHEMBL5573859 | 0.86 | CCR5 (0.44) | CCR5NSD3RIPK1SLC18A3SIGMAR1 | |
| SCHEMBL5573869 | 0.83 | GPR119 (0.44) | CCR5 | |
| SCHEMBL5573862 | 0.83 | GPR119 (0.44) | CCR5 | |
| SCHEMBL14571163 | 0.76 | RIPK1 (0.43) | CCR5NSD3RIPK1SLC18A3SIGMAR1 | |
| SCHEMBL4610216 | 0.74 | CCR5 (0.40) | CCR5NSD3RIPK1 | |
| SCHEMBL5575040 | 0.74 | MEN1 (0.47) | CCR5NSD3 | |
| SCHEMBL4597932 | 0.74 | MEN1 (0.47) | CCR5NSD3 | |
| SCHEMBL4598546 | 0.73 | ALDH1A1 (0.41) | CCR5RIPK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | CCR5 1/4885NSD3 4084/4885RIPK1 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.