Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1449025 | 0.89 | REN (0.42) | ALDH1A1MMP1MMP2CCR5 | |
| SCHEMBL1450242 | 0.82 | MMP1 (0.39) | CTSSMMP1MMP2CCR5OPRM1 | |
| SCHEMBL265605 | 0.81 | CCR5 (0.39) | OPRD1MMP1FCER2MMP2CCR5 | |
| SCHEMBL265370 | 0.79 | MMP1 (0.39) | CTSSMMP1MMP2CCR5 | |
| Hydrochloric Acid SCHEMBL266228 | 0.79 | MMP1 (0.38) | CTSSMMP1MMP2CCR5 | |
| SCHEMBL2492378 | 0.74 | CTSS (0.37) | HPGDSMN1; SMN2ALDH1A1CTSSKMT2A | |
| SCHEMBL266063 | 0.72 | CTSS (0.43) | HPGDALDH1A1CTSSKMT2A | |
| SCHEMBL1449086 | 0.70 | SLC6A2 (0.41) | CTSSMMP1MMP2KMT2AOPRK1 | |
| SCHEMBL21172315 | 0.69 | KMT2A (0.55) | KMT2A | |
| SCHEMBL21172402 | 0.69 | KMT2A (0.55) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845104-A1 | PAR-2 AGONIST | Kowa Company. Ltd. (JP) | 2007-10-17 | — | — | EP | claimed |