SCHEMBL5574191

SCHEMBL5574191

O=S(=O)(Cl)c1ccccc1CCC(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.34
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYSLTR2 Q9NS75 1/20 0.33
CYSLTR1 Q9Y271 1/20 0.33
EPHX2 P34913 1/20 0.32
TRPV4 Q9HBA0 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
CTSB P07858 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9444005 0.88 HSD11B1 (0.36) HSD11B1ALDH1A1HSD17B10TDP1TRPV4
SCHEMBL8610746 0.82 CA2 (0.44) PTGES2CA2
SCHEMBL29469857 0.82 CA2 (0.44) PTGES2CA2
SCHEMBL776735 0.82 MYC (0.39) HSD11B1CYSLTR2CYSLTR1EPHX2MEN1
SCHEMBL9444041 0.82 CTSB (0.33) HSD11B1ALDH1A1HSD17B10TDP1PTGES2
SCHEMBL8905176 0.81 HSD11B1 (0.36) HSD11B1EPHX2MEN1KMT2ACA2
SCHEMBL8905178 0.81 MYC (0.38) HSD11B1CYSLTR2CYSLTR1EPHX2MEN1
SCHEMBL11254980 0.77 ALDH1A1 (0.38) ALDH1A1HSD17B10TDP1TRPV4PTGES2
SCHEMBL1415489 0.76 MGLL (0.37) ALDH1A1HSD17B10TDP1TRPV4PTGES2
SCHEMBL11249042 0.76 TAAR1 (0.37) ALDH1A1CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113336679-A Synthesis method of triflusulfuron-methyl intermediate 江苏省农用激素工程技术研究中心有限公司 2021-09-03 CN claimed
CN-113336679-A Synthesis method of triflusulfuron-methyl intermediate 江苏省农用激素工程技术研究中心有限公司 2021-09-03 CN disclosed
EP-1814849-A1 HETEROCYCLIC COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR Abbott GmbH & Co. KG (DE) 2007-08-08 EP disclosed
WO-2006040182-A1 HETEROCYCLIC COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR ABBOTT GMBH & CO. KG (DE) 2006-04-20 WO disclosed
US-5637763-A Process for the preparation of substituted benzenes and benzene sulfonic acid and derivatives thereof and a process for the preparation of N,N'-substituted ureas CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
EP-0584043-B1 Process for the preparation of substituted benzenes and benzene sulfonic acid and derivatives thereof and a process for the preparation of N'N-substituted ureas CIBA GEIGY AG (CH) 1996-10-30 EP disclosed
US-5508402-A Process for the preparation of N,N'-substituted ureas CIBA-GEIGY CORPORATION (US) 1996-04-16 US disclosed
EP-0584043-A1 Process for the preparation of substituted benzenes and benzene sulfonic acid and derivatives thereof and a process for the preparation of N'N-substituted ureas CIBA-GEIGY AG (CH) 1994-02-23 EP disclosed