Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267329 | 0.85 | MCHR1 (0.35) | CYP1A2CYP3A4CYP3A5SCN9APTGES | |
| SCHEMBL5272120 | 0.84 | MCHR1 (0.34) | CYP1A2CYP3A4CYP3A5SCN9APTGES | |
| SCHEMBL5573963 | 0.84 | CYP1A2 (0.34) | CYP1A2CYP3A4CYP3A5SCN9APTGES | |
| SCHEMBL5350625 | 0.84 | CYP1A2 (0.34) | CYP1A2CYP3A4CYP3A5SCN9APTGES | |
| SCHEMBL5571402 | 0.83 | KDM4E (0.43) | CYP1A2PTGESPPARDMCHR1MEN1 | |
| SCHEMBL5338178 | 0.80 | PTGES (0.33) | SCN9APTGESPTPN5PPARDMCHR1 | |
| SCHEMBL5571416 | 0.80 | MLYCD (0.38) | PTGESPPARDMCHR1MEN1KMT2A | |
| SCHEMBL5570207 | 0.79 | GPR35 (0.36) | CYP1A2CYP3A4CYP3A5ALOX5APFEN1 | |
| SCHEMBL5573431 | 0.79 | MCHR1 (0.37) | CYP1A2CYP3A4CYP3A5SCN9AALOX5AP | |
| SCHEMBL5574783 | 0.78 | KDM4E (0.44) | CYP1A2PPARDMCHR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841736-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077367-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |