Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573963 | 0.86 | CYP1A2 (0.34) | CYP1A2PTGESPTPN5MCHR1CYP3A4 | |
| SCHEMBL5267329 | 0.85 | MCHR1 (0.35) | CYP1A2PTGESPTPN5MCHR1CYP3A4 | |
| SCHEMBL5272120 | 0.84 | MCHR1 (0.34) | CYP1A2PTGESPTPN5MCHR1CYP3A4 | |
| SCHEMBL5574807 | 0.84 | CYP1A2 (0.34) | CYP1A2PTGESPTPN5MCHR1CYP3A4 | |
| SCHEMBL5571402 | 0.82 | KDM4E (0.43) | CYP1A2PTGESMCHR1MEN1KMT2A | |
| SCHEMBL5570207 | 0.79 | GPR35 (0.36) | CYP1A2PTPN5MCHR1CYP3A4CYP3A5 | |
| SCHEMBL5573431 | 0.79 | MCHR1 (0.37) | CYP1A2PTPN5MCHR1CYP3A4CYP3A5 | |
| SCHEMBL5571416 | 0.79 | MLYCD (0.38) | PTGESMCHR1MEN1KMT2A | |
| SCHEMBL5338178 | 0.79 | PTGES (0.33) | PTGESPTPN5MCHR1MEN1KMT2A | |
| SCHEMBL5506955 | 0.78 | KMT2A (0.39) | PTPN5MCHR1ALOX5APFEN1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838669-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077365-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |