⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511102 | 0.85 | TEAD4 (0.52) | — | |
| SCHEMBL10992491 | 0.85 | L3MBTL1 (0.42) | — | |
| SCHEMBL104811 | 0.83 | APP (0.32) | — | |
| SCHEMBL5385145 | 0.75 | CYP2A6 (0.59) | — | |
| SCHEMBL3975069 | 0.75 | RXRA (0.50) | — | |
| SCHEMBL3149415 | 0.73 | MMP3 (0.38) | — | |
| SCHEMBL9445826 | 0.73 | GRM5 (0.64) | — | |
| SCHEMBL4457730 | 0.73 | GRM5 (0.64) | — | |
| SCHEMBL219074 | 0.73 | ALDH1A1 (0.58) | — | |
| SCHEMBL18050322 | 0.73 | ALDH1A1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4822 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | claimed |
| CN-118271331-A | Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation | 赣江中药创新中心 | 2024-07-02 | — | — | CN | claimed |
| CN-113929695-B | Sulfimide psoralen derivatives, and preparation method and application thereof | 南开大学 | 2024-06-07 | — | — | CN | claimed |
| CN-117945876-A | Benzophenone compound and preparation method and application thereof | 湖北理工学院 | 2024-04-30 | — | — | CN | claimed |
| CN-114751860-B | Synthesis method of nuciferine or nuciferine derivative, nuciferine derivative and application of nuciferine derivative | 华侨大学 | 2024-03-15 | — | — | CN | claimed |
| CN-117510500-A | Preparation method of asperazepanones alkaloid and application of asperazepanones alkaloid as anti-inflammatory drug | 中国海洋大学 | 2024-02-06 | — | — | CN | claimed |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2024-02-01 | — | — | US | claimed |
| CN-117050043-A | 3-phenyl dibenzofuran compound and preparation method and application thereof | 中国海洋大学 | 2023-11-14 | — | — | CN | claimed |
| CN-113651863-B | Unsaturated thioglycoside compound and selective synthesis method and application thereof | 华东师范大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116947865-A | Synthesis method of risperidone intermediate and Li Sipu blue intermediate | 奥锐特药业(天津)有限公司 | 2023-10-27 | — | — | CN | claimed |
| US-4230698-A | ANTITUMOR AGENTS, VIRICIDES, AND MICROBIOCIDES | RESEARCH CORPORATION (US) | 1980-10-28 | — | — | US | claimed |
| US-4217357-A | Inhibition of thromboxane synthetase with 3-(imidazol-1-ylalkyl)indoles | PFIZER INC. (US) | 1980-08-12 | — | — | US | claimed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | claimed |
| US-4198205-A | SULFONIC ACID-FREE DISPERSE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | claimed |
| US-4148791-A | DISPERSE DYES | SANDOZ LTD. (CH) | 1979-04-10 | — | — | US | claimed |
| US-4119718-A | 3-Amino-2-oxy-propoxy-substituted isothiazoles | MERCK & CO., INC. (US) | 1978-10-10 | — | — | US | claimed |
| US-4100350-A | 3-Substituted propanoic acid derivatives | LILLY INDUSTRIES LTD. (GB) | 1978-07-11 | — | — | US | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |
| US-3987026-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | claimed |
| US-3933827-A | CYTOSTATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-01-20 | — | — | US | claimed |