(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL5575129

C(=Cc1ccccc1)c1ccccc1.CCCO.CCCO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.52
TTR P02766 1/20 0.48
ALOX5 P09917 1/20 0.48
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
CHAT P28329 2/20 0.48
MAOB P27338 2/20 0.48
NPC1 O15118 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TRPA1 O75762 2/20 0.46
GLA P06280 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
NFE2L2 Q16236 1/20 0.46
CYP19A1 P11511 1/20 0.46
MAOA P21397 1/20 0.46
GRM5 P41594 1/20 0.45
PAM P19021 1/20 0.45
HDAC3 O15379 1/20 0.44
TNKS O95271 1/20 0.44
HDAC4 P56524 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL5576205 1.00 RELA (0.52) RELATTRALOX5PTGS1PTGS2
(Z)-1,2-Diphenylethene SCHEMBL5575127 1.00 RELA (0.52) RELATTRALOX5PTGS1PTGS2
(Z)-1,2-Diphenylethene SCHEMBL1679623 0.90 NFE2L2 (0.56) RELATTRALOX5PTGS1PTGS2
(Z)-1,2-Diphenylethene SCHEMBL2067523 0.87 MAOB (0.55) RELATTRALOX5PTGS1PTGS2
(Z)-1,2-Diphenylethene SCHEMBL27870109 0.87 MAOB (0.55) RELATTRALOX5PTGS1PTGS2
Cinnamaldehyde SCHEMBL28719830 0.83 LMNA (0.69) ALOX5MAOBNPC1L3MBTL1TRPA1
Cinnamaldehyde SCHEMBL28719829 0.83 LMNA (0.69) ALOX5MAOBNPC1L3MBTL1TRPA1
(Z)-1,2-Diphenylethene SCHEMBL28882092 0.82 RELA (0.54) RELACHATMAOBTRPA1TDP1
Styrene SCHEMBL8333425 0.81 ALDH1A1 (0.64) RELANPC1L3MBTL1TDP1HDAC8
Benzaldehyde SCHEMBL3860024 0.81 ALDH1A1 (0.64) ALOX5MAOBNPC1L3MBTL1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070242592-A1 Three-dimensional optical memory MEMPILE INC. (US) 2007-10-18 US disclosed
EP-1269469-B1 THREE-DIMENSIONAL OPTICAL MEMORY MEMPILE INC (US) 2006-10-04 EP disclosed
US-7011925-B2 Three-dimensional optical memory MEMPILE INC. (US) 2006-03-14 US disclosed
US-20040022165-A1 Three-dimensional optical memory MEMPILE, INC. 2004-02-05 US disclosed
EP-1269469-A2 THREE-DIMENSIONAL OPTICAL MEMORY Mempile Inc. (US) 2003-01-02 EP disclosed
WO-2001073779-A2 THREE-DIMENSIONAL OPTICAL MEMORY MEMPILE INC. (US) 2001-10-04 WO disclosed