SCHEMBL557549

SCHEMBL557549

CO[Si](CCCn1c(=O)[nH]c(=O)[nH]c1=O)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 4/20 0.35
PDE4A P27815 3/20 0.35
ADORA2A P29274 3/20 0.35
PDE4B Q07343 3/20 0.35
PDE4C Q08493 3/20 0.35
PDE4D Q08499 3/20 0.35
ADORA3 P0DMS8 3/20 0.35
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
ALDH1A1 P00352 3/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PDE2A O00408 1/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31
TLR7 Q9NYK1 1/20 0.31
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28636308 0.95 ALDH1A1 (0.32) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL21772430 0.89 ATM (0.30) ATM
SCHEMBL4131368 0.86 APEX1 (0.42) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL28429834 0.84 PDE4A (0.34) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL4129111 0.83 ADORA2B (0.36) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL4141489 0.81 PDE4A (0.33) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL22472307 0.80 ADORA2B (0.38) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL22472338 0.79 ADORA2B (0.40) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL155052 0.79 LMNA (0.33) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL15066191 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325034-A Synthesis method and application of high-performance moisture-curing organic silicon resin 广东吉美帮新材料有限公司 2024-07-12 CN claimed
CN-114921187-B Packaging adhesive film and preparation method and application thereof 苏州赛伍应用技术股份有限公司 2024-06-25 CN claimed
CN-117050570-B Star-shaped organosiloxane modified graphene filler and preparation method of reinforced anticorrosive paint thereof 江西省科学院应用化学研究所 2024-05-17 CN claimed
CN-118027641-A Aging-resistant high-adhesive-strength polycarbonate reinforcing material and preparation method and application thereof 东莞市奥能工程塑料有限公司 2024-05-14 CN claimed
CN-118027845-A Infrared reflection transparent packaging adhesive film and preparation method and application thereof 浙江赛伍应用技术有限公司 2024-05-14 CN claimed
CN-117089318-B Organic silicon die-bonding adhesive and preparation method and application thereof 北京康美特科技股份有限公司 2024-05-10 CN claimed
CN-117987049-A Halogen-free flame-retardant acrylate adhesive for flexible printed circuit board, preparation method thereof and adhesive film 华烁电子材料(武汉)有限公司 2024-05-07 CN claimed
CN-117777732-A Packaging material and preparation method and application thereof 华为技术有限公司 2024-03-29 CN claimed
CN-115926667-B EPE type three-layer co-extrusion adhesive film and preparation method and application thereof 苏州赛伍应用技术股份有限公司 2024-03-15 CN claimed
CN-117467364-A Packaging adhesive film and preparation method and application thereof 浙江赛伍应用技术有限公司 2024-01-30 CN claimed
US-20120031558-A1 METHOD OF CONSTRUCTING A BASKETBALL BACKBOARD LIFETIME PRODUCTS, INC. (US) 2012-02-09 US claimed
EP-1553992-B1 PROCESS FOR LUBRICATING HYPODERMIC NEEDLES WITH RADIATION CURABLE SILICON MATERIAL COVIDIEN AG (CH) 2010-06-09 EP claimed
US-7354628-B2 Medical device lubricant comprising radiation curable silicon material COVIDIEN AG (CH) 2008-04-08 US claimed
EP-1209201-B1 Process for the manufacture of organopolysiloxane compositions DOW CORNING SA (BE) 2005-11-02 EP claimed
US-20050203201-A1 Medical device lubricant comprising radiation curable silicon material CARDINAL HEALTH IRELAND UNLIMITED COMPANY (IE) 2005-09-15 US claimed
EP-1553992-A1 MEDICAL DEVICE LUBRICANT COMPRISING RADIATION CURABLE SILICON MATERIAL Sherwood Services, AG (CH) 2005-07-20 EP claimed
WO-2004009146-A1 MEDICAL DEVICE LUBRICANT COMPRISING RADIATION CURABLE SILICON MATERIAL SHERWOOD SERVICES AG (CH) 2004-01-29 WO claimed
US-20020091221-A1 Process for the manufacturing of organopolysiloxane compositions DOW CORNING S.A. (BE) 2002-07-11 US claimed
EP-1209201-A1 Process for the manufacture of organopolysiloxane compositions DOW CORNING S.A. (BE) 2002-05-29 EP claimed
EP-0569186-B1 Silicone additive systems GEN ELECTRIC (US) 2000-08-09 EP claimed