Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | UBE2I | P63279 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576048 | 1.00 | L3MBTL1 (0.44) | L3MBTL1KDM4CALDH1A1KDM4EPPARG | |
| SCHEMBL5573930 | 0.83 | CCR5 (0.41) | ALDH1A1MAPTNSD3CCR5TDP1 | |
| SCHEMBL5573927 | 0.83 | CCR5 (0.41) | ALDH1A1MAPTNSD3CCR5TDP1 | |
| SCHEMBL5575431 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTHSD17B10NSD3CCR5 | |
| SCHEMBL5575418 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTHSD17B10NSD3CCR5 | |
| SCHEMBL4611139 | 0.80 | USP30 (0.49) | L3MBTL1KDM4CALDH1A1KDM4EMAPT | |
| SCHEMBL4611146 | 0.80 | USP30 (0.49) | L3MBTL1KDM4CALDH1A1KDM4EMAPT | |
| SCHEMBL4608568 | 0.75 | FADS1 (0.40) | MAPTNSD3CCR5RECQLMEN1 | |
| SCHEMBL4608571 | 0.75 | FADS1 (0.40) | MAPTNSD3CCR5RECQLMEN1 | |
| SCHEMBL4598041 | 0.74 | SLC18A3 (0.39) | NSD3CCR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309690-A | Chemokine receptor binding compounds | ANORMED INC (CA) | 2008-11-19 | — | — | CN | disclosed |
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | L3MBTL1 3305/4885KDM4C 3646/4885ALDH1A1 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.