SCHEMBL5576280

SCHEMBL5576280

C=CC(=O)NCOC(=O)C(=C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.45
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
MAPK1 P28482 1/20 0.45
THRB P10828 1/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
TGM2 P21980 2/20 0.33
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16805860 0.86 TSHR (0.54) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL28104400 0.83 ALDH1A1 (0.37) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL7776385 0.82 ALDH1A1 (0.50) TSHRALDH1A1TDP1MAPK1ZDHHC20
SCHEMBL3818410 0.81 THRB (0.46) TSHRALDH1A1TDP1MAPK1THRB
SCHEMBL11337160 0.81 TSHR (0.57) TSHRALDH1A1TDP1MAPK1THRB
SCHEMBL822676 0.79 TSHR (0.48) TSHRALDH1A1TDP1MAPK1THRB
SCHEMBL17345313 0.79 TSHR (0.50) TSHRALDH1A1TDP1MAPK1THRB
SCHEMBL5856959 0.78 ALDH1A1 (0.42) TSHRALDH1A1TDP1MAPK1THRB
SCHEMBL17250046 0.78 THRB (0.48) TSHRALDH1A1TDP1THRBPOLB
SCHEMBL17347982 0.78 TSHR (0.53) TSHRALDH1A1TDP1MAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070134410-A1 Preparation of particles by hydrolysis of a metal cation in the presence of a polymer ANTHONY OLIVIER 2007-06-14 US claimed
EP-2725009-B1 POLYMERIZABLE COMPOUND, INK CARTRIDGE CONTAINING INK INCLUDING THE POLYMERIZABLE COMPOUND, INKJET RECORDING APPARATUS USING THE INK CARTRIDGE, AND PRINT FORMED BY INK INCLUDING THE POLYMERIZABLE COMPOUND RICOH CO LTD (JP) 2018-04-25 EP disclosed
US-9267043-B2 Polymerizable compound, ink cartridge containing ink including the polymerizable compound, inkjet recording apparatus using the ink cartridge, and print formed by ink including the polymerizable compound RICOH COMPANY, LTD. (JP) 2016-02-23 US disclosed
US-9267043-B2 Polymerizable compound, ink cartridge containing ink including the polymerizable compound, inkjet recording apparatus using the ink cartridge, and print formed by ink including the polymerizable compound RICOH COMPANY, LTD. (JP) 2016-02-23 US disclosed
US-20070134410-A1 Preparation of particles by hydrolysis of a metal cation in the presence of a polymer ANTHONY OLIVIER 2007-06-14 US disclosed
US-6069191-A COPOLYMER OF PERFLUOROALKYL GROUP-CONTAINING ETHYLENICALLY UNSATURATED MONOMER AND/OR POLYDIMETHYLSILOXANE GROUP CONTAINING ETHYLENICALLY UNSATURATED MONOMER AND ETHYLENICALLY UNSATURATED MONOMER COPOLYMERIZABLE THEREWITH; RELEASE AGENTS DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-05-30 US disclosed
US-4734319-A TIN OXIDE AND HARDENING RESIN SUMITOMO CHEMICAL CO., LTD. (JP) 1988-03-29 US disclosed
US-4080476-A ACRYLIC POLYMERS DATASCOPE CORPORATION (US) 1978-03-21 US disclosed