SCHEMBL17345313

SCHEMBL17345313

C=CC(=O)NCCCOC(=O)C(=C)C

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.50
ZDHHC20 Q5W0Z9 1/20 0.50
ZDHHC2 Q9UIJ5 1/20 0.50
THRB P10828 1/20 0.43
TGM2 P21980 2/20 0.40
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
MAPK1 P28482 1/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.37
CYP3A4 P08684 1/20 0.36
ACHE P22303 6/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21496227 0.97 TSHR (0.47) TSHRZDHHC20ZDHHC2THRBTGM2
SCHEMBL17347982 0.95 TSHR (0.53) TSHRZDHHC20ZDHHC2THRBTGM2
SCHEMBL17347983 0.94 TSHR (0.56) TSHRZDHHC20ZDHHC2THRBTGM2
SCHEMBL18855009 0.94 TSHR (0.56) TSHRZDHHC20ZDHHC2THRBTGM2
SCHEMBL23983133 0.91 TGM2 (0.44) TSHRZDHHC20ZDHHC2TGM2ACHE
SCHEMBL3818410 0.90 THRB (0.46) TSHRZDHHC20ZDHHC2THRBTGM2
SCHEMBL8079136 0.87 TSHR (0.42) TSHRZDHHC20ZDHHC2THRBTGM2
SCHEMBL17522070 0.85 THRB (0.54) TSHRZDHHC20ZDHHC2THRBTGM2
SCHEMBL17345014 0.85 THRB (0.54) TSHRZDHHC20ZDHHC2THRBTGM2
SCHEMBL14165100 0.85 THRB (0.54) TSHRZDHHC20ZDHHC2THRBTGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230270630-A1 COMPOSITION FOR DENTAL ATTACHMENT KURARAY NORITAKE DENTAL INC. (JP) 2023-08-31 US claimed
EP-4193985-A1 COMPOSITION FOR DENTAL ATTACHMENT Kuraray Noritake Dental Inc. (JP) 2023-06-14 EP claimed
CN-116096339-A Dental attachment composition 可乐丽则武齿科株式会社 2023-05-09 CN claimed
WO-2022030642-A1 COMPOSITION FOR DENTAL ATTACHMENT クラレノリタケデンタル株式会社 2022-02-10 WO claimed
EP-3388046-B1 DENTAL ADHESIVE KURARAY NORITAKE DENTAL INC (JP) 2020-06-10 EP claimed
US-10456333-B2 Dental adhesive KURARAY NORITAKE DENTAL INC. (JP) 2019-10-29 US claimed
US-20180360696-A1 DENTAL ADHESIVE KURARAY NORITAKE DENTAL INC. (JP) 2018-12-20 US claimed
EP-3388046-A1 DENTAL ADHESIVE Kuraray Noritake Dental Inc. (JP) 2018-10-17 EP claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4659730-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-12-10 EP disclosed
EP-4649938-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-11-19 EP disclosed
EP-4613256-A1 DENTAL ADHESIVE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-09-10 EP disclosed
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
EP-4578439-A1 DENTAL ADHESIVE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-07-02 EP disclosed
EP-3156034-A1 SELF-ADHESIVE DENTAL COMPOSITE RESIN Kuraray Noritake Dental Inc. (JP) 2017-04-19 EP disclosed
CN-106456452-A Self-adhesive dental composite resin 可乐丽则武齿科株式会社 2017-02-22 CN disclosed
CN-106413667-A Dental adhesive 可乐丽则武齿科株式会社 2017-02-15 CN disclosed
CN-106413666-A Dental cement 可乐丽则武齿科株式会社 2017-02-15 CN disclosed
WO-2015190099-A1 DENTAL ADHESIVE クラレノリタケデンタル株式会社 2015-12-17 WO disclosed
WO-2015190101-A1 SELF-ADHESIVE DENTAL COMPOSITE RESIN クラレノリタケデンタル株式会社 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE CDH1, MACF1, ICAM1 TSHR 4548/4885ZDHHC20 288/4885ZDHHC2 2065/4885
US-20180360696-A1 DENTAL ADHESIVE PTK2, CDH1, CAD TSHR 4078/4885ZDHHC20 4116/4885ZDHHC2 4379/4885
US-20230270630-A1 COMPOSITION FOR DENTAL ATTACHMENT ITGA1, ITGA2, PPA1 TSHR 4298/4885ZDHHC20 3318/4885ZDHHC2 3019/4885
US-10456333-B2 Dental adhesive PTK2, CDH1, CAD TSHR 4078/4885ZDHHC20 4116/4885ZDHHC2 4379/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL TSHR 4185/4885ZDHHC20 2747/4885ZDHHC2 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.