Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | WNT3A | P56704 | 3/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14513384 | 0.92 | ALDH1A1 (0.34) | SMN1; SMN2L3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL5576782 | 0.90 | PTGS1 (0.35) | PTGDR2DRD2SLC6A3PTGES2SLC6A2 | |
| SCHEMBL4860428 | 0.90 | CTNNB1 (0.40) | SMN1; SMN2L3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL5577134 | 0.89 | PTGS1 (0.35) | PTGDR2DRD2SLC6A3PTGES2 | |
| SCHEMBL5576935 | 0.86 | PTGDR2 (0.38) | SMN1; SMN2L3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL4861300 | 0.85 | NPC1 (0.41) | SMN1; SMN2L3MBTL1ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL5576999 | 0.85 | PTGDR2 (0.37) | SMN1; SMN2L3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL4851983 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL5313774 | 0.83 | PTGS1 (0.35) | DRD2SLC6A3PTGES2 | |
| SCHEMBL4855046 | 0.83 | CTNNB1 (0.39) | SMN1; SMN2L3MBTL1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099986-A1 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099986-A1 | Preventives/remedies for urinary disturbance | REN, GLS, ATP6V1B1 | SMN1; SMN2 1537/4885L3MBTL1 1737/4885ALDH1A1 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.