Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | GAA | P10253 | 7/20 | 0.62 |
| ▸ | GLA | P06280 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074031 | 0.81 | KDM4E (0.71) | KDM4EGAAGLASMN1; SMN2ATM | |
| SCHEMBL1060529 | 0.81 | ALDH1A1 (0.53) | KDM4EGAAGLASMN1; SMN2ATM | |
| SCHEMBL27820459 | 0.79 | KDM4E (0.69) | KDM4EGAAGLASMN1; SMN2ATM | |
| SCHEMBL619826 | 0.79 | ALDH1A1 (0.51) | KDM4EGAAGLASMN1; SMN2ATM | |
| SCHEMBL21092381 | 0.78 | KDM4E (0.58) | KDM4EGAAGLASMN1; SMN2ATM | |
| SCHEMBL572613 | 0.77 | GAA (0.57) | KDM4EGAAGLASMN1; SMN2ATM | |
| SCHEMBL17154414 | 0.77 | KDM4E (0.61) | KDM4EGAAGLASMN1; SMN2ATM | |
| SCHEMBL9350852 | 0.77 | KDM4E (0.57) | KDM4EGAAGLASMN1; SMN2ATM | |
| SCHEMBL13134235 | 0.75 | KDM4E (0.55) | KDM4EGAAGLASMN1; SMN2ATM | |
| SCHEMBL8440112 | 0.74 | ALOX15 (0.53) | KDM4EGAASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035320-A1 | POLYACRIDINE NUCLEIC ACID DELIVERY PEPTIDE COMPLEXES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2012-02-09 | — | — | US | claimed |
| US-20120035320-A1 | POLYACRIDINE NUCLEIC ACID DELIVERY PEPTIDE COMPLEXES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035320-A1 | POLYACRIDINE NUCLEIC ACID DELIVERY PEPTIDE COMPLEXES | NUP205, PABPC1, SARNP | KDM4E 4760/4885GAA 2929/4885GLA 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.