Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579264 | 0.73 | KMT2A (0.45) | KMT2ACA2MMP8MMP2MMP9 | |
| SCHEMBL6891449 | 0.73 | POLB (0.50) | KMT2ACA2MMP8MMP2MMP9 | |
| SCHEMBL6451238 | 0.72 | ALDH1A1 (0.55) | KMT2ACA2MMP8MMP2MMP9 | |
| SCHEMBL8421941 | 0.70 | KMT2A (0.56) | KMT2ACA2MEN1POLBL3MBTL1 | |
| SCHEMBL15547058 | 0.69 | BRD4 (0.50) | KMT2ACA2MMP8MMP2MMP9 | |
| SCHEMBL10344222 | 0.69 | KMT2A (0.51) | KMT2ACA2MEN1POLBL3MBTL1 | |
| SCHEMBL7303827 | 0.68 | MTNR1A (0.45) | KMT2ACA2MMP8MMP2MMP9 | |
| SCHEMBL10344224 | 0.67 | KMT2A (0.54) | KMT2ACA2MMP8MMP2MMP9 | |
| SCHEMBL18272440 | 0.67 | KMT2A (0.50) | KMT2ACA2MMP8MMP2MMP9 | |
| SCHEMBL1598705 | 0.67 | LMNA (0.57) | KMT2ACA2MMP8MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |