Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580169 | 0.83 | — | — | |
| Trifluoroacetic Acid SCHEMBL7105511 | 0.77 | CTSD (0.44) | KDM4EKDM5CPHF8KDM2ACTSD | |
| Trifluoroacetic Acid SCHEMBL8722643 | 0.76 | KDM4E (0.48) | KDM4EKDM5CPHF8KDM2ACTSD | |
| Trifluoroacetic Acid SCHEMBL15453390 | 0.75 | ACLY (0.39) | KDM4EALDH1A1LMNAGMNNUSP2 | |
| Trifluoroacetic Acid SCHEMBL7625248 | 0.72 | KDM4E (0.35) | KDM4EKDM5CPHF8KDM2ACTSD | |
| Trifluoroacetic Acid SCHEMBL5793900 | 0.72 | TSHR (0.59) | KDM4EKDM5CPHF8KDM2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL17867577 | 0.72 | DGAT1 (0.36) | KDM4EKDM5CPHF8KDM2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL10587540 | 0.70 | DGAT1 (0.34) | KDM4EALDH1A1LMNACYP1A2ALOX15 | |
| Trifluoroacetic Acid SCHEMBL31050235 | 0.69 | CA2 (0.36) | ALDH1A1TP53CYP1A2POLBTHPO | |
| Trifluoroacetic Acid SCHEMBL28224030 | 0.69 | CA2 (0.36) | ALDH1A1TP53CYP1A2POLBTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070264667-A1 | Method and system for assaying transferase activity | GELLIBOLIAN ROBERT | 2007-11-15 | — | — | US | disclosed |
| WO-2005024380-A9 | METHOD AND SYSTEM FOR ASSAYING TRANSFERASE ACTIVITY | GELLIBOLIAN ROBERT (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005024380-A2 | METHOD AND SYSTEM FOR ASSAYING TRANSFERASE ACTIVITY | GELLIBOLIAN ROBERT (US) | 2005-03-17 | — | — | WO | disclosed |