SCHEMBL8404261

SCHEMBL8404261

O=C(Nc1ccc(N2C(=O)C=CC2=O)cc1)c1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.59
MGLL Q99685 2/20 0.54
FAAH O00519 1/20 0.54
KMT2A Q03164 6/20 0.52
MEN1 O00255 5/20 0.52
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 4/20 0.52
HSP90AA1 P07900 4/20 0.52
LMNA P02545 4/20 0.52
PKM P14618 3/20 0.52
HPGD P15428 3/20 0.52
NPSR1 Q6W5P4 3/20 0.52
KDM4E B2RXH2 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HTT P42858 2/20 0.52
G6PD P11413 1/20 0.52
ALOX12 P18054 1/20 0.52
CCR6 P51684 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52
PLEC Q15149 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268629 1.00 DDAH1 (0.59) DDAH1MGLLFAAHKMT2AMEN1
SCHEMBL12268614 0.95 PTPN1 (0.56) DDAH1MGLLFAAHKMT2AMEN1
SCHEMBL11937128 0.92 HSP90AA1 (0.60) DDAH1MGLLFAAHKMT2AMEN1
SCHEMBL13306325 0.84 PGR (0.58) MGLLKMT2AMEN1
SCHEMBL12268724 0.84 PGR (0.58) MGLLKMT2AMEN1
SCHEMBL5580375 0.83 MGLL (0.60) DDAH1MGLLFAAHTDP1HSP90AA1
SCHEMBL12268727 0.83 PGR (0.48) MGLLKMT2AMEN1ALDH1A1LMNA
SCHEMBL13306326 0.83 PGR (0.48) MGLLKMT2AMEN1ALDH1A1LMNA
SCHEMBL10968265 0.81 DDAH1 (0.63) DDAH1MGLLFAAHALDH1A1TDP1
SCHEMBL8194022 0.81 HSP90AA1 (0.59) DDAH1MGLLFAAHKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659800-B1 Polyimide precursor composition, polyimide composition and process for the production of said polyimide composition CENTRAL GLASS CO LTD (JP) 1999-06-23 EP disclosed
US-5840369-A SCREEN PRINTING POLYIMIDE PRECURSOR INK ON SUBSTRATE, REMOVING SOLVENT, THERMALLY CURING INK TO FORM POLYIMIDE RELIEF PATTERN FILM CENTRAL GLASS CO., LTD. (JP) 1998-11-24 US disclosed
US-5686525-A THIXOTROPIC SCREEN PRINTING INK COMPRISING A HEAT TREATED POLYAMIC ACID SOLUTION OBTAINED BY REACTION OF AROMATIC TETRACARBOXYLIC ACID, DIAMINE AND A MALEIMIDE; RELIEF IMAGES CENTRAL GLASS COMPANY, LTD. (JP) 1997-11-11 US disclosed
US-5478918-A Low stress polyimide composition and precursor composition solution of same CENTRAL GLASS COMPANY, LIMITED (JP) 1995-12-26 US disclosed
EP-0659800-A1 Polyimide precursor composition, polyimide composition and process for the production of said polyimide composition CENTRAL GLASS COMPANY, LIMITED (JP) 1995-06-28 EP disclosed