Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | F13A1 | P00488 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590420 | 0.83 | POLB (0.62) | POLBMAPTTP53KDM1AMAOA | |
| SCHEMBL23917849 | 0.83 | ALDH1A1 (0.69) | POLBMAPTTP53KDM1AMAOA | |
| SCHEMBL5582508 | 0.83 | POLB (0.58) | POLBMAPTTP53KDM1AMAOA | |
| SCHEMBL8867533 | 0.82 | POLB (0.64) | POLBMAPTTP53KDM1AMAOA | |
| SCHEMBL3968088 | 0.82 | POLB (0.64) | POLBMAPTTP53KDM1AMAOA | |
| SCHEMBL21054940 | 0.81 | POLB (0.62) | POLBMAPTTP53KDM1AMAOA | |
| SCHEMBL19682897 | 0.81 | POLB (0.62) | POLBMAPTTP53KDM1AMAOA | |
| SCHEMBL592715 | 0.80 | POLB (0.66) | POLBMAPTTP53KDM1AMAOA | |
| SCHEMBL27475998 | 0.80 | KDM4E (0.49) | KDM4EF13A1MAPTMEN1KMT2A | |
| SCHEMBL8428000 | 0.80 | LMNA (0.69) | MAPTMEN1KMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066526-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-07-20 | — | — | US | disclosed |
| US-11066526-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-07-20 | — | — | US | disclosed |
| US-10954316-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-03-23 | — | — | US | disclosed |
| US-20190010113-A1 | METHOD FOR CLEAVING AMIDE BONDS | GALDERMA S.A. (CH) | 2019-01-10 | — | — | US | disclosed |
| WO-2017207564-A1 | METHOD FOR CLEAVING AMIDE BONDS | GALDERMA S.A. (CH) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017114859-A1 | METHOD FOR CLEAVING AMIDE BONDS | GALDERMA S.A. (CH) | 2017-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190010113-A1 | METHOD FOR CLEAVING AMIDE BONDS | DNPEP, NAAA, ASPH | POLB 1122/4885KDM4E 1693/4885F13A1 1144/4885 |
| US-11066526-B2 | Method for cleaving amide bonds | DNPEP, NAAA, ASPH | POLB 1122/4885KDM4E 1693/4885F13A1 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.