Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4809727 | 0.85 | CA12 (0.37) | CYP2C19MEN1KMT2ACYP1A2TSHR | |
| SCHEMBL16552936 | 0.81 | CA12 (0.55) | CYP2C19MEN1KMT2ACYP1A2TSHR | |
| SCHEMBL11775833 | 0.79 | CYP2C19 (0.36) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL16431024 | 0.78 | CA12 (0.39) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL7971206 | 0.78 | CA12 (0.53) | CYP2C19MEN1KMT2ACYP1A2TSHR | |
| SCHEMBL10540660 | 0.78 | — | — | |
| SCHEMBL11826637 | 0.77 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL1459003 | 0.77 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL28667034 | 0.77 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL15386571 | 0.76 | TSHR (0.42) | CYP2C19MEN1GLAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10844269-B2 | Sealing fluid for setting a packer | TOTAL E&P DANMARK A/S (DK) | 2020-11-24 | — | — | US | disclosed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2019-06-13 | — | — | US | disclosed |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX INC (US) | 2018-09-27 | — | — | US | disclosed |
| US-20180237682-A1 | SEALING FLUID FOR SETTING A PACKER | TOTAL E&P DANMARK A/S (DK) | 2018-08-23 | — | — | US | disclosed |
| EP-3356356-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| US-9920234-B2 | Sealing fluid for setting a packer | MAERSK OLIE OG GAS A/S (DK) | 2018-03-20 | — | — | US | disclosed |
| US-9732071-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2017-04-06 | — | — | US | disclosed |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | SENOMYX INC (US) | 2017-03-30 | — | — | US | disclosed |
| EP-2805009-B1 | SEALING FLUID FOR SETTING A PACKER | MAERSK OLIE & GAS (DK) | 2017-03-01 | — | — | EP | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| EP-1852479-B1 | METHOD FOR PROTECTING DYNAMICALLY LOADED SURFACES AND COATING THEREFOR | M & S METALLSCHUTZ GMBH (DE) | 2016-04-13 | — | — | EP | disclosed |
| US-20150021028-A1 | SEALING FLUID FOR SETTING A PACKER | MAERSK OLIE OG GAS A/S (DK) | 2015-01-22 | — | — | US | disclosed |
| EP-2805009-A1 | SEALING FLUID FOR SETTING A PACKER | MAERSK OLIE OG GAS A/S (DK) | 2014-11-26 | — | — | EP | disclosed |
| WO-2013107789-A1 | SEALING FLUID FOR SETTING A PACKER | MÆRSK OLIE OG GAS A/S (DK) | 2013-07-25 | — | — | WO | disclosed |
| EP-1852479-A1 | Method for protecting dynamically loaded surfaces and coating therefor | M + S Metallschutz GmbH (DE) | 2007-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | CYP2C19 1076/4885MEN1 3045/4885GLA 2207/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | CYP2C19 4193/4885MEN1 1052/4885GLA 3806/4885 |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | CYP2C19 4389/4885MEN1 1247/4885GLA 3913/4885 |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | CYP2C19 4389/4885MEN1 1247/4885GLA 3913/4885 |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | TRPA1, PDE6G, PDE6D | CYP2C19 140/4885MEN1 404/4885GLA 756/4885 |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | CYP2C19 4389/4885MEN1 1247/4885GLA 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.