Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583447 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL5583522 | 0.92 | DRD2 (0.33) | DRD2DRD1DRD4DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL3397056 | 0.83 | — | — | |
| SCHEMBL15871033 | 0.77 | PNMT (0.33) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL15870968 | 0.69 | DRD2 (0.36) | DRD2DRD1DRD4DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL31564483 | 0.68 | NOS3 (0.33) | — | |
| SCHEMBL22432603 | 0.62 | DRD2 (0.33) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL4625362 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL8030722 | 0.62 | CYP11B2 (0.43) | DRD2DRD4DRD3 | |
| SCHEMBL22504309 | 0.62 | CYP2A6 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7195129-B2 | Inner container for household devices | BASELL POLYOLEFINE GMBH (DE) | 2007-03-27 | — | — | US | disclosed |
| US-6794019-B2 | MOLDING MATERIALS; USING COORDINATION CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2004-09-21 | — | — | US | disclosed |
| US-20030022009-A1 | Molding materials; using coordination catalysts | EQUISTAR CHEMICALS, LP | 2003-01-30 | — | — | US | disclosed |