Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 4/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PARG | Q86W56 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583717 | 0.92 | KDR (0.48) | KDRBRAFSTK39RAF1MAPT | |
| SCHEMBL5583625 | 0.91 | STK39 (0.57) | KDRBRAFSTK39RAF1MAPT | |
| SCHEMBL4701462 | 0.89 | MAPT (0.52) | KDRBRAFRAF1TDO2MAPT | |
| SCHEMBL5583752 | 0.85 | MAPT (0.57) | KDRRAF1TDO2MAPT | |
| SCHEMBL14284578 | 0.85 | KDR (0.51) | KDRBRAFRAF1MAPTKDM4E | |
| SCHEMBL14284629 | 0.83 | RAB9A (0.55) | RAF1MAPTKDM4E | |
| SCHEMBL5583759 | 0.83 | KDR (0.47) | KDRBRAFMAPTAXL | |
| SCHEMBL14284616 | 0.82 | KDR (0.49) | KDRBRAFRAF1TDO2MAPT | |
| SCHEMBL14284615 | 0.82 | LMNA (0.54) | KDRRAF1TDO2MAPT | |
| SCHEMBL5583862 | 0.82 | KDR (0.55) | KDRBRAFRAF1MAPTAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |