Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.63 |
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583719 | 0.83 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11729473 | 0.79 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL5583568 | 0.79 | MEN1 (0.54) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5583672 | 0.78 | SCN9A (0.54) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14284458 | 0.78 | EGLN1 (0.41) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL14637696 | 0.77 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL29764989 | 0.77 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL2237038 | 0.77 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL5583820 | 0.77 | RAB9A (0.60) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5583684 | 0.77 | KDM4E (0.55) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |