Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 5/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284595 | 0.94 | KDR (0.55) | SCN9AKDRPDGFRAKDM4ERAB9A | |
| SCHEMBL5583684 | 0.88 | KDM4E (0.55) | KDRPDGFRAKDM4ENPC1RAB9A | |
| SCHEMBL5586513 | 0.87 | KMT2A (0.47) | SCN9AKDRPDGFRAKDM4ENPC1 | |
| SCHEMBL5583581 | 0.86 | KDR (0.49) | SCN9AKDRPDGFRANPC1RAB9A | |
| SCHEMBL5583719 | 0.86 | NPC1 (0.53) | KDRPDGFRAKDM4ENPC1RAB9A | |
| SCHEMBL5583592 | 0.86 | GRM4 (0.54) | KDRPDGFRAKDM4ENPC1RAB9A | |
| SCHEMBL5583666 | 0.85 | PNLIP (0.62) | KDRPDGFRAMEN1KMT2AMAPT | |
| SCHEMBL5583655 | 0.84 | RAB9A (0.53) | KDRPDGFRAKDM4ENPC1RAB9A | |
| SCHEMBL5583568 | 0.84 | MEN1 (0.54) | KDRPDGFRAKDM4ENPC1RAB9A | |
| SCHEMBL5583578 | 0.84 | SMN1; SMN2 (0.53) | KDRNPC1RAB9AHDAC8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |