Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | EBP | Q15125 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585642 | 0.95 | LTA4H (0.32) | LTA4HGRIN1GRIN2AGRIN2BSIGMAR1 | |
| SCHEMBL5586062 | 0.90 | LTA4H (0.36) | LTA4HGRIN1GRIN2AGRIN2BTSHR | |
| SCHEMBL5585764 | 0.87 | OPRM1 (0.32) | LTA4HSIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL5585687 | 0.84 | OPRM1 (0.32) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5585662 | 0.82 | SIGMAR1 (0.31) | SIGMAR1EBP | |
| SCHEMBL5586065 | 0.82 | SIGMAR1 (0.33) | LTA4HGRIN1GRIN2AGRIN2BSIGMAR1 | |
| SCHEMBL5585752 | 0.80 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL5585758 | 0.78 | — | — | |
| SCHEMBL5585801 | 0.77 | MAPK1 (0.32) | LTA4HSIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL1134144 | 0.77 | DRD2 (0.33) | SIGMAR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836238-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM | Bridgestone Corporation (JP) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006076629-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM | BRIDGESTONE CORPORATION (JP) | 2006-07-20 | — | — | WO | disclosed |