SCHEMBL5586065

SCHEMBL5586065

CCCCN1CCCCC1(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.33
DRD2 P14416 3/20 0.33
DRD3 P35462 3/20 0.33
LTA4H P09960 1/20 0.33
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
EBP Q15125 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1134144 0.94 DRD2 (0.33) SIGMAR1DRD2DRD3EBP
SCHEMBL5585752 0.90 SIGMAR1 (0.31) SIGMAR1DRD2DRD3
SCHEMBL5137676 0.89 ALOX5 (0.33) SIGMAR1LTA4H
SCHEMBL5585804 0.86 DRD2 (0.35) SIGMAR1DRD2DRD3EBP
SCHEMBL5586038 0.82 BDKRB2 (0.31) DRD2
SCHEMBL5585727 0.82 LTA4H (0.34) SIGMAR1LTA4HGRIN1GRIN2AGRIN2B
SCHEMBL5585888 0.80 SIGMAR1 (0.30) SIGMAR1
SCHEMBL5585819 0.79
SCHEMBL5585642 0.78 LTA4H (0.32) SIGMAR1LTA4HGRIN1GRIN2AGRIN2B
SCHEMBL5585662 0.78 SIGMAR1 (0.31) SIGMAR1DRD2DRD3EBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1836238-A1 FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM Bridgestone Corporation (JP) 2007-09-26 EP disclosed
WO-2006076629-A1 FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM BRIDGESTONE CORPORATION (JP) 2006-07-20 WO disclosed