Sugi Predict

Sugi Predict / Compounds / SCHEMBL1574024

SCHEMBL1574024

SCHEMBL1574024

CC1c2ccccc2C(C)C(C)C1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR3 P46089 2/20 0.36
▸ MEN1 O00255 4/20 0.35
▸ KMT2A Q03164 4/20 0.35
▸ USP2 O75604 1/20 0.34
▸ AADAT Q8N5Z0 1/20 0.33
▸ NOS3 P29474 1/20 0.32
▸ NOS1 P29475 1/20 0.32
▸ NOS2 P35228 1/20 0.32
▸ HTR2A P28223 1/20 0.32
▸ HTR2C P28335 1/20 0.32
▸ HTR2B P41595 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ ACHE P22303 1/20 0.32
▸ HTR5A P47898 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11674515 0.77 EDNRA (0.47) —
SCHEMBL31740975 0.77 EDNRA (0.47) —
SCHEMBL9113014 0.75 MAOA (0.39) GPR3MEN1KMT2AGAA
SCHEMBL3236685 0.75 AADAT (0.39) GPR3MEN1KMT2AAADATNOS3
SCHEMBL3236677 0.75 AADAT (0.39) GPR3MEN1KMT2AAADATNOS3
SCHEMBL28348254 0.75 MEN1 (0.33) GPR3MEN1KMT2AUSP2AADAT
SCHEMBL3236671 0.75 AADAT (0.39) GPR3MEN1KMT2AAADATNOS3
SCHEMBL18080870 0.73 MAOA (0.37) GPR3MEN1KMT2AUSP2AADAT
SCHEMBL31070318 0.72 GPR3 (0.39) GPR3MEN1KMT2ANOS3NOS1
SCHEMBL18887229 0.72 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1713779-B1 INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES SANOFI AVENTIS DEUTSCHLAND (DE) 2011-04-13 — — EP claimed
US-20090215824-A1 INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE SENSITIVE LIPASE SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2009-08-27 — — US claimed
EP-1713779-A1 INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES Sanofi-Aventis Deutschland GmbH (DE) 2006-10-25 — — EP claimed
US-20050197348-A1 Indazole derivatives as inhibitors of hormone sensitive lipase AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2005-09-08 — — US claimed
WO-2005073199-A1 INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2005-08-11 — — WO claimed
EP-0691962-A1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1996-01-17 — — EP claimed
WO-1994022842-A1 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1994-10-13 — — WO claimed
US-4695671-A Tetramethyltetrahydronaphthalene purification process PHILLIPS PETROLEUM COMPANY (US) 1987-09-22 — — US claimed
US-12559467-B2 Organic light emitting device LG CHEM, LTD. (KR) 2026-02-24 — — US disclosed
US-12497415-B2 Polycyclic compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2025-12-16 — — US disclosed
CN-116789625-A Main body material and preparation method thereof, luminescent layer material and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2023-09-22 — — CN disclosed
US-20230114182-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-04-13 — — US disclosed
US-20230092585-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-03-23 — — US disclosed
US-20230090371-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-03-23 — — US disclosed
US-4695671-A Tetramethyltetrahydronaphthalene purification process PHILLIPS PETROLEUM COMPANY (US) 1987-09-22 — — US disclosed
US-4568757-A ACNE, PSORIASIS, ANTITUMOR AGENTS, VITAMIN A TYPE ACTIVITY RESEARCH TRIANGLE INSTITUTE (US) 1986-02-04 — — US disclosed
US-4568757-A ACNE, PSORIASIS, ANTITUMOR AGENTS, VITAMIN A TYPE ACTIVITY RESEARCH TRIANGLE INSTITUTE (US) 1986-02-04 — — US disclosed
US-4178311-A Process for the production of compounds useful in perfumery INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-12-11 — — US disclosed
US-4162256-A Process for the production of compounds useful in perfumery INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-07-24 — — US disclosed
US-4123469-A Process for production of bicyclic compounds INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-10-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497415-B2 Polycyclic compound and organic light-emitting element comprising same CYBA, CRY2, CRY1 GPR3 2062/4885MEN1 1727/4885KMT2A 2595/4885
US-20090215824-A1 INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE SENSITIVE LIPASE LIPE, PNLIP, CEL GPR3 1087/4885MEN1 2534/4885KMT2A 4174/4885
US-20230114182-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, NR2E3 GPR3 2815/4885MEN1 2887/4885KMT2A 1286/4885
US-12559467-B2 Organic light emitting device CRY1, RPS24, ARL1 GPR3 766/4885MEN1 514/4885KMT2A 2913/4885
US-20050197348-A1 Indazole derivatives as inhibitors of hormone sensitive lipase LIPE, PNLIP, CEL GPR3 1087/4885MEN1 2534/4885KMT2A 4174/4885
US-20230092585-A1 ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, PER2 GPR3 2031/4885MEN1 970/4885KMT2A 2234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.